Table 3

Grouping of antibodies into positive and negative staining with separation of categories as shown

AntibodyHistological infectionNo histological infectionSensitivitySpecificity
CRP (liver) diffuse staining
 Positive2010100% (83.2% to 100%)87.5% (78.2% to 93.8%)
 Negative070
CRP (heart) any staining
 Positive18690% (68.3% to 98.5%)92.5% (84.4% to 97.2%)
 Negative274
Interleukin 6 (liver) any staining
 Positive92145% (23.1% to 68.5%)73.8% (62.7% to 83.0%)
 Negative1159
ICAM-1 (liver) any staining
 Positive12660% (36.1% to 80.8%)92.5% (84.4% to 97.2%)
 Negative874
ICAM-1 (heart) diffuse staining
 Positive10050% (27.2% to 72.8%)100.0% (95.5% to 100%)
 Negative1080
  • Sensitive and specificity for each antibody is demonstrated, along with 95% CIs in parentheses.

  • CRP, c-reactive protein.