Table 1

First-line antibiotics and durations used in cost comparison analysis

Indication	Antibiotic	Dose	Duration (days)
Community-acquired pneumonia	Amoxicillin	500 mg tds	5
Community-acquired pneumonia	Clarithromycin	500 mg bd	5
Severe community-acquired pneumonia	Benzylpenicillin	1.2 g qqh	5
Severe community-acquired pneumonia	Levofloxacin	500 mg bd	5
Hospital-acquired pneumonia	Piperacillin—tazobactam	4.5 g tds	5
Pleural empyema	Piperacillin—tazobactam	4.5 g tds	21
Liver abscess	Piperacillin—tazobactam	4.5 g tds	28
Neutropaenic sepsis	Piperacillin—tazobactam	4.5 g tds	14
Sepsis of unknown origin	Amoxicillin	1 g tds	7
	Metronidazole	400 mg tds	7
	Gentamicin	320 mg od	7
Urinary tract infection	Trimethoprim	200 mg bd	3 (women)
Urinary tract infection	Trimethoprim	200 mg bd	5 (men)
Complicated urinary tract infection	Amoxicillin—clavulanic acid	625 mg tds	5
Intra-abdominal infections	Amoxicillin—clavulanic acid	625 mg tds	5
Cellulitis	Flucloxacillin	500 mg qds	7
Septic arthritis and osteomyelitis	Flucloxacillin	2 g qds	28
Septic arthritis and osteomyelitis	Flucloxacillin	2 g qds	42

bd, twice daily; g, gram; mg, milligram; od, once daily; qds, four times daily; qqh, every 4 h; tds, three times daily.