Table 1

First-line antibiotics and durations used in cost comparison analysis

IndicationAntibioticDoseDuration (days)
Community-acquired pneumoniaAmoxicillin500 mg tds5
Clarithromycin500 mg bd5
Severe community-acquired pneumoniaBenzylpenicillin1.2 g qqh5
Levofloxacin500 mg bd5
Hospital-acquired pneumoniaPiperacillin—tazobactam4.5 g tds5
Pleural empyemaPiperacillin—tazobactam4.5 g tds21
Liver abscessPiperacillin—tazobactam4.5 g tds28
Neutropaenic sepsisPiperacillin—tazobactam4.5 g tds14
Sepsis of unknown originAmoxicillin1 g tds7
Metronidazole400 mg tds7
Gentamicin320 mg od7
Urinary tract infectionTrimethoprim200 mg bd3 (women)
5 (men)
Complicated urinary tract infectionAmoxicillin—clavulanic acid625 mg tds5
Intra-abdominal infectionsAmoxicillin—clavulanic acid625 mg tds5
CellulitisFlucloxacillin500 mg qds7
Septic arthritis and osteomyelitisFlucloxacillin2 g qds28
  • bd, twice daily; g, gram; mg, milligram; od, once daily; qds, four times daily; qqh, every 4 h; tds, three times daily.