HPV positivity in 1020 samples stratified by cytology grade and HPV assay
| Cytology | HC2: c/o 1.0 n pos/total % (95% CI) | HC2: c/o 2.0 n pos/total % (95% CI) | rtHPV n pos/total % (95% CI) | AHPV n pos/total % (95% CI) | Cervista n pos/total % (95% CI) | COBAS n pos/total % (95% CI) | Positive by any test % (95 CI) | Number of CIN2+ |
|---|---|---|---|---|---|---|---|---|
| Negative or borderline | 181/955 19.0 (16.5 to 21.6) | 150/955 15.7 (13.5 to 18.2) | 194/955 20.3 (17.8 to 23.0) | 130/955 13.6 (11.5 to 16.0) | 223/955 23.4 (20.7 to 26.2) | 220/955 23.0 (20.4 to 25.8) | 345/955 36.1 (33.1 to 39.3) | 4 |
| Mild | 25/32 78.1 (60.0 to 90.7) | 25/32 78.1 (60.0 to 90.7) | 24/32 75.0 (56.6 to 88.5) | 24/32 75.0 (56.6 to 88.5) | 26/32 81.2 (63.6 to 92.8) | 25/32 78.1 (60.0 to 90.7) | 28/32 87.5 (71.0 to 96.5) | 3 |
| Moderate or severe | 28/33 84.8 (68.1 to 94.9) | 26/33 78.8 (61.1 to 91.0) | 28/33 84.8 (68.1 to 94.9) | 28/33 84.8 (68.1 to 94.9) | 26/33 78.8 (61.1 to 91.0) | 28/33 84.8 (68.1 to 94.9) | 30/33 90.1 (75.7 to 98.1) | 16 |
| Total | 234/1020 22.9 (20.4 to 25.6) | 201/1020 19.7 (17.3 to 22.3) | 246/1020 24.1 (21.5 to 26.9) | 182/1020 17.8 (15.5 to 20.3) | 275/1020 27.0 (24.3 to 29.8) | 273/1020 26.8 (24.1 to 29.6) | 403/1020 39.5 (36.5 to 42.6) | 23 |
AHPV, Aptima HPV Test; CIN, cervical intraepithelial neoplasia; c/o, cut off; HC2, hybrid capture 2 test; rtHPV, real time HPV test.