Summary of immunohistological findings with antibodies to free light chains in 185 renal biopsies and immunoglobulin status of patients (as defined in materials and methods)
| Light chain deposition and immunoglobulin abnormality | No light chain deposition and no immunoglobulin abnormality | No light chain deposition and immunoglobulin abnormality | Light chain deposition and no immunoglobulin abnormality | |
|---|---|---|---|---|
| Amyloid n=41 | 26 (1*) | 11 | 3 (1†, 2*) | 1* |
| Light chain cast nephropathy n=33 | 32 | – | 1* | – |
| Light chain deposition disease n=6 | 6 | – | 0 | – |
| Cryoglobulinaemia n=6 | 4 | – | 2 (1†, 1*) | – |
| Miscellaneous n=3 | 3 | – | 0 | – |
| Neoplastic infiltration n=2 | 0 | – | 2† | – |
| No evidence of renal effects of immunoglobulin abnormality n=31 | 0 | – | 31† | – |
| No immunoglobulin abnormality (excluding amyloid cases) n=63 | – | 62 | – | 1* |
*Considered discordant.
†Not considered discordant, as discussed in text.