Summary of modified-Folpe criteria
Benign | Less than or one worrisome feature (including invasive edge, size ≥5 to <10 cm, mitoses two to three per 50 HPF, lymphovascular invasion) |
Uncertain malignant potential | One worrisome feature that includes isolated marked atypia, size ≥10 cm or mitotic count greater than or four per 50 HPF |
Malignant | Any necrosis or two worrisome features |
Caution should be exercised when evaluating tumours exhibiting LVI as the sole worrisome feature, as there are very limited data on outcomes in patients with such tumours.
HPF, high power field.