Patient demographics
| All patients | COP | AFOP | GOP | p Value | |
|---|---|---|---|---|---|
| Number of patients | 61 | 36 | 10 | 15 | n.s. |
| Average age (years) | 61.5 | 60.3 | 59.6 | 62.6 | n.s. |
| Male sex (%) | 35 (57) | 25 (69) | 4 (40) | 6 (40) | n.s. |
| Caucasian (%) | 53 (87) | 30 (83) | 9 (90) | 14 (93) | n.s. |
| Any history of cancer (%) | 43 (70) | 25 (69) | 10 (100) | 8 (53) | 0.05 |
| Active cancer (%) | 16 (26) | 10 (28) | 5 (50) | 1 (7) | n.s. |
| Prior radiation (%) | 18 (30) | 9 (25) | 6 (60) | 3 (20) | n.s. |
| Median time from radiation (months) | 13.5 | 7.9 | 4.5 | 143 | n.s. |
| Prior chemotherapy (%) | 27 (44) | 15 (42) | 8 (80) | 4 (27) | 0.03 |
| Median time from chemotherapy (months) | 3.0 | 2.7 | 2.5 | 76.5 | n.s. |
| Ever smoker | 36 (59) | 19 (53) | 5 (50) | 12 (80) | n.s. |
| Ex-smoker (% of all smokers) | 32 (89) | 16 (84) | 4 (80) | 12 (100) | n.s. |
| Active smoker (% of all smokers) | 4 (11) | 3 (16) | 1 (20) | 0 (0) | n.s. |
| Median pack-years | 30 | 45 | 30 | 25.5 | n.s. |
| Any respiratory symptom (%) | 32 (52) | 20 (56) | 6 (60) | 6 (40) | n.s. |
| Respiratory failure (%) | 3 (5) | 1 (3) | 2 (20) | 0 (0) | n.s. |
| Medication prescribed (%)* | 15 (25) | 10 (28) | 3 (30) | 2 (13) | n.s. |
| Steroids (% of all medications) | 14 (93) | 9 (90) | 3 (100) | 2 (100) | n.s. |
| Macrolides (% of all medications) | 4 (27) | 2 (20) | 0 | 2 (100) | n.s. |
| Azathioprine (% of all medications) | 3 (20) | 3 (20) | 0 | 0 | n.s. |
| Death (%) | 14 (23) | 9 (25) | 4 (40) | 1 (7) | n.s. |
| Death due to organising pneumonia (% of all deaths) | 1 (7) | 1 (11) | 0 (0) | 0 (0) | n.s. |
*Seven patients received multiple medication forms (five with COP, two with GOP).
AFOP, acute fibrinous and organising pneumonia; COP, cryptogenic organising pneumonia; GOP, granulomatous organising pneumonia.