PDAC profiling studies performed on blood, serum, plasma, bile, pancreatic juice or stool
| miRNAs upregulated | miRNAs downregulated | References |
|---|---|---|
| miR-205, miR-210, miR-492, miR-1247 | 62 | |
| miR-10b, miR-155, miR-106b, miR-30c, miR-212 | 61 | |
| miR-27a-3p, miR-16-5p, miR-15-5p | 68 | |
| miR-21, miR-210, miR-155, miR-196a | 77 | |
| miR-20a, miR-21, miR-24, miR-25, miR-99a, miR-185, miR-191 | 74§ | |
| miR-26b, miR-34a, miR-122, miR-126*, miR-145, miR-150, miR-223, miR-505, miR-636, miR-885.5p | 66† | |
| miR-16, miR-21, miR-155, miR-181a, miR-181b, miR-196a, miR-210 | 73§ | |
| miR-21 | 78§ | |
| miR-21, miR-155 | 53 | |
| miR-18a | 76 | |
| miR-221 | miR-375 | 71 |
| miR-21, miR-155 | miR-216 | 19 |
§miRNAs differently expressed in PDAC and CP.
†miR-150,miR-636, miR-145 and miR-223 are sufficient to identify PDAC lesions.
CP, chronic pancreatitis; miRNA, microRNA; PDAC, pancreatic ductal adenocarcinoma.