Table 9

Clinical studies of lactobacilli showing efficacy for treatment of gastrointestinal pathologies

BacteriaDosePathologyRef. (Design)
VSL#3®
(L. casei, L. plantarum, L. acidophilus, L. delbrueckii subsp bulgaricus, B. longum, B. breve, B. infantis and St. thermophilus)
5×1011 CFU/g (3 g) (total)Chronic pouchitis230(open study)
Yakult®
(L. casei Shirota)
6.5×109 CFUConstipation231(open study)
L plantarum SN13T2×108 CFUConstipation232(double-blind, randomised study)
VSL#3®
(L. casei, L. plantarum, L. acidophilus, L. delbrueckii subsp bulgaricus, B. longum, B. breve, B. infantis and St. thermophilus)
5×1011 CFU/g (3 g) (total)Ulcerative colitis233(open study)