Summary of mismatch repair (MMR) immunohistochemistry, showing the distribution of positive and negative cases for each antibody in both labs
| Laboratory | MMR marker | Positive cases (%) | Negative cases (%) | No result or equivocal (%) |
|---|---|---|---|---|
| Leeds | MLH1 | 90 (92.8) | 6 (6.2) | 1 (1.0) |
| Cardiff | MLH1 | 90 (92.8) | 6 (6.2) | 1 (1.0) |
| Leeds | MSH2 | 95 (97.9) | 1 (1.0) | 1 (1.0) |
| Cardiff | MSH2 | 96 (99.0) | 1 (1.0) | 0 |
| Leeds | MSH6 | 92 (94.8) | 3 (3.1) | 2 (2.1) |
| Cardiff | MSH6 | 94 (96.9) | 3 (3.1) | 0 |
| Leeds | PMS2 | 88 (90.7) | 7 (7.2) | 2 (2.1) |
| Cardiff | PMS2 | 89 (91.8) | 7 (7.2) | 1 (1.0) |
For each protein, the same number of negative cases was identified in both labs.