Table 3

Documented autoantibodies produced during parvovirus B19 infection

AutoantibodyClinical presentationFunctional significance of autoantibodyCase report referenceStudy reference
Rheumatoid factorRheumatoid arthritisYes86, 186216, 217
Anti-cyclic citrullinated peptide antibodyRheumatoid arthritisYes218
Anti-cardiolipin antibodyGlomerulonephritisYes178
Systemic lupus erythematosusYes219
Juvenile idiopathic arthritisYes220
Anti-phosphatidylserine antibodyJuvenile idiopathic arthritisYes220
Anti-β2-glycoprotein I antibodyJuvenile idiopathic arthritisYes220
Anti-erythrocyte antibodyEvans syndromeYes172, 173
Donath-Landsteiner antibody (anti-blood group P antigen)Autoimmune haemolytic anaemiaYes204
Anti-JK(a) antibodyAutoimmune haemolytic anaemiaYes221
Anti-nuclear antibodyGlomerulonephritisYes178133, 216
Proteinase-3 antineutrophil cytoplasmic antibodyGlomerulonephritisYes178, 222
Anti-glomerular basement membrane antibodyGlomerulonephritisYes178
Myeloperoxidase-antineutrophil cytoplasmic antibodyGlomerulonephritisYes223
Anti-ganglioside GM1 and GD1b antibodiesGuillain-Barré syndromeYes154
Insulinoma antigen-2 (IA-2) antibodyType 1 diabetes mellitusYes179
GAD antibodyType 1 diabetes mellitusYes179, 180 186
Anti-TPO antibodyHashimoto’s thyroiditisYes181
Anti-thyroglobulin antibodyHashimoto’s thyroiditisYes182
Anti-TSH antibodyGraves diseaseYes186, 187
Anti-dsDNA antibody224
Anti-ssDNA antibody224
Cytotoxic anti-lymphocyte antibody224
Anti-mitochondrial antibody216
Anti-smooth muscle antibody216
Anti-gastric parietal cell antibody216
Anti-reticulin antibody216

  • GAD, glutamic acid decarboxylase; TPO, thyroid peroxidase; TSH, thyroid stimulating hormone.