Table 6

Articles reporting survival by Ki-67 using a cut-off of 5% and 20%

AuthorPatient demographicKi-67 notes
Ki-67 labelling index (%)5-Year survival (%)No.
Martin-Perez et al28481 consecutive patients, (184 stained), pancreatic neuroendocrine tumours (NETs) and peripancreatic NETs.
Surgical resection and biopsy
≤585.7118
>5–2046.346
>2017.420
Bertani et al29110 consecutive patients (41 patients stained) primary NET with unresectable liver metastases. Surgical resection only≤5
>5–20
90
58
10
21
>202010
Scarpa et al20274 consecutive patients (237 patients stained) Pancreatic endocrine tumours operated on. Surgical resection and biopsy≤591166
>5–205293
>201230
Hentic et al2145 consecutive patients, metastatic digestive endocrine carcinoma. All with liver metastases. Surgical resection and biopsy≤59519
>5–205223
>20333