Baseline values in the reference period (3 November 2012 to 14 September 2013)
| Vitamins | Testing once | Retesting at least once | Statistical analysis | ||
|---|---|---|---|---|---|
| Inpatients | Outpatients | Inpatients | Outpatients | ||
| Vitamin D | |||||
| Cases/total, No (%) | 2218/2991 (74.2) | 19 885/23 739 (83.8) | 773/2991 (25.8) | 3854/23 739 (16.2) | χ2=171.4, p<0.001 |
| M/F, No (% of F) | 945/1273 (57.4) | 5204/14 681 (73.5) | 354/419 (54.2) | 1317/2537 (65.8) | χ2=2.37, p=0.12 for inpatients; χ2=103.7, p<0.001 for outpatients |
| Age (years), mean±SE | 44.6±0.7* | 58.5±0.1* | 34.4±1.1* | 59.9±0.3* | F=2906.8, p<0.001 |
| Vitamin D (nmol/L), median (IQR), | 45 (24–68)* | 59 (38–79)* | 50 (25–75)* | 62 (40–83)* | χ2=1777.6, p<0.001 |
| Vitamin D12 | |||||
| Cases/total, No (%) | 1828/2040 (89.6) | 3166/3632 (87.2) | 212/2040 (10.4) | 466/3632 (12.8) | χ2=7.37 p=0.007 |
| M/F, No (% of F) | 925/903 (49.4) | 1151/2015 (63.6) | 106/106 (50.0) | 190/276 (59.2) | χ2=0.03, p=0.87 for inpatients, χ2=3.40, p=0.07 for outpatients |
| Age (years), mean±SE | 61.2±0.6* | 64.4±0.4* | 61.3±1.9* | 70.7±0.8* | F=93.42, p<0.001 |
| Vitamin B12 (ng/L), median (IQR) | 449 (326–644)† | 409 (301–561) | 411 (256–636)† | 395 (284–591) | χ2=179.4, p<0.001 |
| Folate | |||||
| Cases/total, No (%) | 1873/2087 (89.7) | 3155/3583 (88.1) | 214/2087 (10.3) | 428/3583 (11.9) | χ2=3.75 P=0.05 |
| M/F, No (% of F) | 921/952 (50.8) | 1133/2022 (64.1) | 112/102 (47.7) | 171/257 (60.1) | χ2=85.5, p<0.001for inpatients, χ2=8.87, p=0.003 for outpatients |
| Age (years), mean±SE | 58.8±0.6* | 63.2±0.4* | 51.1±2.2* | 70.4±0.9* | F=146.03, p<0.001 |
| Folate (µg/L), median (IQR) | 6.9 (5.1–9.7)‡ | 7.2 (5.4–9.9) | 6.6 (4.9–11.3) | 7.1 (5.1–11.1) | χ2=18.2, p<0.001 |
SI conversion factors: to convert vitamin B12 to pmol/L, multiply values by 0.7378; to convert folate to nmol/L, multiply values by 2.266.
One-way analysis of variance was used to compare means and Kruskal–Wallis to compare medians.
Bonferroni's test was used for pairwise comparisons.
*p<0.001 as compared with all the others.
†p<0.001 as compared with outpatients testing both once and twice.
‡p<0.001 as compared with outpatients testing once.