Table 1

Baseline values in the reference period (3 November 2012 to 14 September 2013)

VitaminsTesting onceRetesting at least onceStatistical analysis
InpatientsOutpatientsInpatientsOutpatients
Vitamin D
Cases/total, No (%)2218/2991 (74.2)19 885/23 739 (83.8)773/2991 (25.8)3854/23 739 (16.2)χ2=171.4, p<0.001
M/F, No (% of F)945/1273 (57.4)5204/14 681 (73.5)354/419 (54.2)1317/2537 (65.8)χ2=2.37, p=0.12 for inpatients; χ2=103.7, p<0.001 for outpatients
Age (years), mean±SE44.6±0.7*58.5±0.1*34.4±1.1*59.9±0.3*F=2906.8, p<0.001
Vitamin D (nmol/L), median (IQR),45 (24–68)*59 (38–79)*50 (25–75)*62 (40–83)*χ2=1777.6, p<0.001
Vitamin D12
Cases/total, No (%)1828/2040 (89.6)3166/3632 (87.2)212/2040 (10.4)466/3632 (12.8)χ2=7.37 p=0.007
M/F, No (% of F)925/903 (49.4)1151/2015 (63.6)106/106 (50.0)190/276 (59.2)χ2=0.03, p=0.87 for inpatients, χ2=3.40, p=0.07 for outpatients
Age (years), mean±SE61.2±0.6*64.4±0.4*61.3±1.9*70.7±0.8*F=93.42, p<0.001
Vitamin B12 (ng/L), median (IQR)449 (326–644)†409 (301–561)411 (256–636)†395 (284–591)χ2=179.4, p<0.001
Folate
Cases/total, No (%)1873/2087 (89.7)3155/3583 (88.1)214/2087 (10.3)428/3583 (11.9)χ2=3.75 P=0.05
M/F, No (% of F)921/952 (50.8)1133/2022 (64.1)112/102 (47.7)171/257 (60.1)χ2=85.5, p<0.001for inpatients, χ2=8.87, p=0.003 for outpatients
Age (years), mean±SE58.8±0.6*63.2±0.4*51.1±2.2*70.4±0.9*F=146.03, p<0.001
Folate (µg/L), median (IQR)6.9 (5.1–9.7)‡7.2 (5.4–9.9)6.6 (4.9–11.3)7.1 (5.1–11.1)χ2=18.2, p<0.001
  • SI conversion factors: to convert vitamin B12 to pmol/L, multiply values by 0.7378; to convert folate to nmol/L, multiply values by 2.266.

  • One-way analysis of variance was used to compare means and Kruskal–Wallis to compare medians.

  • Bonferroni's test was used for pairwise comparisons.

  • *p<0.001 as compared with all the others.

  • †p<0.001 as compared with outpatients testing both once and twice.

  • ‡p<0.001 as compared with outpatients testing once.