Table 4

Spearman's correlation analysis for associations between MED12 and ER protein expression*

 All casesFibroadenomasPhyllodes tumours
Stromal MED12 expressionEpithelial MED12 expressionStromal MED12 expressionEpithelial MED12 expressionStromal MED12 expressionEpithelial MED12 expression
Epithelial ERα0.137 (p=0.063)0.198 (p=0.007)†0.089 (p=0.377)0.246 (p=0.013)†0.155 (p=0.159)0.142 (p=0.200)
Epithelial ERβ in nucleus0.060 (p=0.419)0.090 (p=0.227)0.061 (p=0.544)0.092 (p=0.362)0.002 (p=0.988)0.023 (p=0.838)
Epithelial ERβ in cytoplasm0.109 (p=0.142)0.034 (p=0.652)0.150 (p=0.135)0.081 (p=0.425)−0.014 (p=0.897)−0.175 (p=0.114)
Stromal ERβ in nucleus0.132 (p=0.075)0.055 (p=0.463)0.156 (p=0.122)0.011 (p=0.912)0.082 (p=0.459)0.005 (p=0.965)
Stromal ERβ in cytoplasm0.089 (p=0.231)0.042 (p=0.577)0.198 (p=0.049)†0.089 (p=0.377)−0.036 (p=0.747)−0.041 (p=0.714)
  • *MED12, ERα and ERβ expression measured in H-scores as continuous data.

  • †Statistically significant.

  • ER, oestrogen receptor.