Spearman's correlation analysis for associations between MED12 and ER protein expression*
| All cases | Fibroadenomas | Phyllodes tumours | ||||
|---|---|---|---|---|---|---|
| Stromal MED12 expression | Epithelial MED12 expression | Stromal MED12 expression | Epithelial MED12 expression | Stromal MED12 expression | Epithelial MED12 expression | |
| Epithelial ERα | 0.137 (p=0.063) | 0.198 (p=0.007)† | 0.089 (p=0.377) | 0.246 (p=0.013)† | 0.155 (p=0.159) | 0.142 (p=0.200) |
| Epithelial ERβ in nucleus | 0.060 (p=0.419) | 0.090 (p=0.227) | 0.061 (p=0.544) | 0.092 (p=0.362) | 0.002 (p=0.988) | 0.023 (p=0.838) |
| Epithelial ERβ in cytoplasm | 0.109 (p=0.142) | 0.034 (p=0.652) | 0.150 (p=0.135) | 0.081 (p=0.425) | −0.014 (p=0.897) | −0.175 (p=0.114) |
| Stromal ERβ in nucleus | 0.132 (p=0.075) | 0.055 (p=0.463) | 0.156 (p=0.122) | 0.011 (p=0.912) | 0.082 (p=0.459) | 0.005 (p=0.965) |
| Stromal ERβ in cytoplasm | 0.089 (p=0.231) | 0.042 (p=0.577) | 0.198 (p=0.049)† | 0.089 (p=0.377) | −0.036 (p=0.747) | −0.041 (p=0.714) |
*MED12, ERα and ERβ expression measured in H-scores as continuous data.
†Statistically significant.
ER, oestrogen receptor.