Mean differences in MVD, pMVD and VPI according to tumour subtype based on linear regression
| Δ Unadjusted | 95% CI | Δ Adjusted* | 95% CI | Δ Adjusted† | 95% CI | |
|---|---|---|---|---|---|---|
| MVD, microvessels/mm2 | ||||||
| BP | Ref | Ref | Ref | |||
| HER2 type‡ | 14.7 | −3.2 to 32.6 | 12.3 | −5.9 to 30.6 | 8.8 | −9.6 to 27.1 |
| 5NP | 55.7 | 33.8 to 77.5 | 55.9 | 34.1 to 77.7 | 54.3 | 30.3 to 78.3 |
| pMVD, microvessels/mm2 | ||||||
| BP | Ref | Ref | Ref | |||
| HER2 type‡ | 0.6 | −1.3 to 2.6 | 0.6 | −1.4 to 2.5 | 0.5 | −1.5 to 2.5 |
| 5NP | 1.6 | −0.8 to 3.9 | 1.5 | −0.8 to 3.9 | 1.9 | −0.7 to 4.5 |
| VPI, percentage points | ||||||
| BP | Ref | Ref | Ref | |||
| HER2 type‡ | 0.0 | −1.7 to 1.6 | 0.1 | −1.6 to 1.8 | 0.2 | −1.5 to 1.9 |
| 5NP | −0.2 | −2.2 to 1.8 | −0.3 | −2.3 to 1.7 | 0.1 | −2.1 to 2.3 |
*Adjusted for age.
†Adjusted for age, grade and stage.
‡One outlier, which was HER2 type, was excluded from linear regression analyses.
5NP, five negative phenotype; BP, basal phenotype; HER2, human epidermal growth factor receptor 2; MVD, microvessel density; pMVD, proliferating microvessel density; VPI, vascular proliferation index.