Table 1

Summary of patients with isolated anti Ro52 positive antibodies (Ro52+Ro60−) in this study population (n=97)

CategoryNumberAge rangeSex (M:F)Clinical conditions (number)
Autoimmune7127–867:64

  1. UCTD (14)

  2. RA (13)

  3. SS (10)

  4. SLE (8)

  5. DLE (2)

  6. SSC (3)

  7. Vasculitis (2)

  8. AIH (4)

  9. PBC (3)

  10. ILD (2)

  11. Myasthenia gravis, hypothyroidism (2)

  12. Lichen planus (1)

  13. Bullous pemphigoid (1)

  14. Hypothyroidism (1)

  15. Miscellaneous

    1. Granulomatous CVID, PA (1)

    2. Raynaud’s (1)

    3. Psoriatic arthritis (1)

    4. PMR (1)

    5. Raynaud’s, myopathy (1)

Other systemic diseases2331–916:17

  1. Musculoskeletal: osteoarthritis, gout

  2. Cardiovascular: antiphospholipid syndrome, cardiac arrhythmia

  3. Neoplastic: paraproteinaemia, neoplasms

  4. Dermatological: asteatotic dermatitis, Jessner’s benign lymphocytic infiltrate

  5. Infections

  6. Miscellaneous: neuropathy, acute generalised exanthematous pustulosis

No specific diagnosis323–470:3Severe hair loss (1)
Arthralgia (1)
Ganglion, bronchial hyperactivity (1)
Total9721–91

  • AIH, autoimmune hepatitis; CVID, common variable immunodeficiency disorders; DLE, discoid lupus erythematosus; ILD, Interstitial lung disease; PA, pernicious anaemia; PBC, primary biliary cirrhosis; PMR, polymyalgia rheumatica; RA, rheumatoid arthritis; SLE, systemic lupus erythematosus; SS, Sjögren’s syndrome; SSC, systemic sclerosis; UCTD, undifferentiated connective diseases/inflammatory polyarthritis.