Types and locations of mutations detected in CEBPA gene
| Mutation | CCS (count/%) | CEBNX (count/%) | TMSP (count/%) | |||||||||||||||
| TAD1 | TAD2 | DBD | bZIP | Others | Total | TAD1 | TAD2 | DBD | bZIP | Others | Total | TAD1 | TAD2 | DBD | bZIP | Others | Total | |
| Insertion | 0 | 1 | 2 | 0 | 0 | 3 (10.3%) | 0 | 1 | 2 | 0 | 0 | 3 (9.4%) | 1 | 0 | 2 | 0 | 0 | 3 (10.34%) |
| Deletions | 3 | 4 | 3 | 0 | 3 | 13 (44.8%) | 3 | 4 | 3 | 0 | 3 | 13 (40.6%) | 2 | 4 | 2 | 0 | 2 | 10 (34.48%) |
| Duplications | 2 | 2 | 4 | 0 | 1 | 9 (31.0%) | 3 | 2 | 4 | 0 | 1 | 10 (31.3%) | 2 | 0 | 4 | 0 | 1 | 7 (24.14%) |
| Substitution | 2 | 0 | 1 | 0 | 1 | 4 (13.8%) | 2 | 1 | 2 | 0 | 1 | 6 (18.8%) | 1 | 3 | 1 | 1 | 3 | 9 (31.03%) |
| Total | 7 (24.14%) | 7 (24.14%) | 10 (34.84%) | 0 | 5 (17.24%) | 29 | 8 (25.0%) | 8 (25.0%) | 11 (34.4%) | 0 | 5 (15.6%) | 32 | 6 (20.69%) | 7 (24.14%) | 9 (31.03%) | 1 (3.45%) | 6 (20.69%) | 29 |
ARD, alternatereaddepth; bZIP, basic leucine zipper; CCS, conventional capillary sequencing; CEBNX, CEBPA-specific Nextera XT; DBD, DNA-bindingdomain; NA, not available; TAD1, transactivationdomain1; TAD2, transactivationdomain2; TMSP, TruSight Myeloid Sequencing Panel; TRD, totalreaddepth; VAF, variant allele frequencies.