Cancers and frequency of p16 inactivation (adapted from Liggett and Sidransky7)
Cancer type | % homozygous deletion | % mutation |
Oesophagus | 20 | 30 |
Pancreas | 30 | 30 |
Non-small cell lung | 20 | 15 |
Head and neck | 50 | 10 |
Glioma | 60 | <5 |
Bladder | 45 | <5 |
Mesothelioma | 50 | <5 |
T-ALL | 50 | <5 |
Melanoma | 25 | <5 |
Ovarian | 10 | <5 |
Sarcomas | 10 | <5 |