Table 1

Overview of scoring strategies

Strategy	Scoring	Positivity definition
I	H&E score	≥CIN2
II	H&E score	≥CIN3
III	Combined H&E and non-objectified IHC score	≥CIN2
IV	Combined H&E and non-objectified IHC score	≥CIN3
V	Immunoscore	≥4
VI	Immunoscore	≥5
VII	Immunoscore	6