Variant caller parameters file for variant calling plug in 5.0 tissue adapted
(B) Sample type in relation to SiRe mutational status results | |||||||
Patients (n=322) | Sample type n | EGFR n | KRAS n | NRAS n | BRAF n | WT n | Inadequate n |
Histology (n=142) | Resection (n=35)* | 7† | 10† | 0 | 2 | 16 | 1 |
Biopsy (n=107)‡ | 13§ | 36† | 0 | 4 | 44 | 11 | |
Citology (n=180) | FNA (n=157) | 23¶ | 44† | 0 | 8 | 67 | 15 |
Brushing/effusion (n=23) | 7§ | 2 | 1 | 0 | 12 | 1 |
*One patient harbouring G12S (KRAS) and D594G (BRAF).
†One patient harbouring two mutations.
‡One patient harbouring ELREA (EGFR) and Q61R (KRAS).
§Two patients harbouring two mutations.
¶Three patients harbouring two mutations.
FNA, fine needle aspirate; WT, wild type.