Prognostic informativeness according to cumulative field areas and sorting strategies
| Visual fields | Cumulative field area (mm2) | Median number of vessels/mm2 (IQR) | HR per 10 vessels increase (95% CI)* | LR test statistic (χ2) | Relative informativeness compared with 10 visual fields (%) |
| MVD-Consecutive | |||||
| 1 | 0.17 | 86.5 (57.7–138.4) | 1.04 (1.01 to 1.06) | 5.69 | 40.5 |
| 2 | 0.35 | 86.5 (57.7–128.3) | 1.05 (1.02 to 1.08) | 10.58 | 75.3 |
| 3 | 0.52 | 80.7 (57.7–121.1) | 1.06 (1.03 to 1.09) | 11.42 | 81.3 |
| 4 | 0.69 | 79.3 (56.2–126.1) | 1.07 (1.04 to 1.10) | 14.36 | 102.2 |
| 5 | 0.87 | 79.6 (55.4–123.4) | 1.07 (1.03 to 1.11) | 13.28 | 94.5 |
| 6 | 1.04 | 77.4 (56.2–122.1) | 1.07 (1.04 to 1.11) | 13.04 | 92.8 |
| 7 | 1.21 | 77.0 (54.8–119.9) | 1.07 (1.03 to 1.11) | 12.74 | 90.7 |
| 8 | 1.39 | 76.0 (54.4–116.8) | 1.07 (1.04 to 1.11) | 12.53 | 89.2 |
| 9 | 1.56 | 74.3 (53.5–114.4) | 1.07 (1.04 to 1.11) | 13.46 | 95.8 |
| 10 | 1.73 | 72.9 (52.8–115.6) | 1.08 (1.04 to 1.12) | 14.05 | |
| MVD-Decreasing | |||||
| 1 | 0.17 | 109.6 (86.5–173.0) | 1.05 (1.03 to 1.07) | 15.38 | 109.5 |
| 2 | 0.35 | 103.8 (77.9–157.1) | 1.06 (1.03 to 1.08) | 16.08 | 114.5 |
| 3 | 0.52 | 99.0 (73.0–150.9) | 1.06 (1.03 to 1.09) | 16.01 | 114.0 |
| 4 | 0.69 | 94.4 (69.2–143.4) | 1.06 (1.03 to 1.09) | 15.69 | 111.7 |
| 5 | 0.87 | 90.5 (66.3–137.2) | 1.07 (1.04 to 1.10) | 15.39 | 109.5 |
| 6 | 1.04 | 86.5 (63.4–132.2) | 1.07 (1.04 to 1.10) | 14.88 | 105.9 |
| 7 | 1.21 | 82.4 (61.0–128.1) | 1.07 (1.04 to 1.11) | 14.65 | 104.3 |
| 8 | 1.39 | 78.6 (58.7–124.0) | 1.07 (1.04 to 1.11) | 14.43 | 102.7 |
| 9 | 1.56 | 75.3 (55.7–119.5) | 1.07 (1.04 to 1.11) | 14.18 | 100.9 |
| 10 | 1.73 | 72.9 (52.8–115.6) | 1.08 (1.04 to 1.12) | 14.05 | |
| MVD-Random | |||||
| 1 | 0.17 | 75.0 (51.9–115.3) | 1.05 (1.01 to 1.08) | 6.71 | 47.8 |
| 2 | 0.35 | 72.1 (53.3–116.8) | 1.07 (1.03 to 1.11) | 12.88 | 91.7 |
| 3 | 0.52 | 71.1 (51.9–118.2) | 1.07 (1.03 to 1.11) | 11.56 | 82.3 |
| 4 | 0.69 | 73.5 (51.9–118.9) | 1.07 (1.03 to 1.11) | 12.81 | 91.2 |
| 5 | 0.87 | 71.5 (50.7–115.3) | 1.08 (1.04 to 1.12) | 14.00 | 99.6 |
| 6 | 1.04 | 71.1 (51.9–114.9) | 1.08 (1.04 to 1.12) | 14.37 | 102.3 |
| 7 | 1.21 | 71.3 (51.9–113.7) | 1.08 (1.04 to 1.12) | 14.09 | 100.3 |
| 8 | 1.39 | 71.7 (52.6–113.5) | 1.08 (1.04 to 1.12) | 14.39 | 102.4 |
| 9 | 1.56 | 72.7 (52.5–115.3) | 1.08 (1.04 to 1.12) | 14.05 | 100.0 |
| 10 | 1.73 | 72.9 (52.8–115.6) | 1.08 (1.04 to 1.12) | 14.05 | |
*Adjusted for year of diagnosis, age at diagnosis, tumour size, lymph node status and molecular subtype.
LR, likelihood ratio; MVD, microvessel density.