Subject characteristics for the study cohort. The event, biochemical recurrence, was defined as PSA above 0.2 ng/mL and person-years is time from radical prostatectomy to event or censoring
| PNI positive men (n=146) | PNI negative men (n=772) | |
| No. (%) | No. (%) | |
| Age | ||
| <54 | 15 (10) | 104 (13) |
| 55–59 | 23 (16) | 125 (16) |
| 60–64 | 53 (36) | 203 (26) |
| ≥65 | 55 (38) | 340 (44) |
| PSA (ng/mL) | ||
| <3 | 17 (12) | 123 (16) |
| 3–5 | 62 (42) | 345 (45) |
| 5–10 | 45 (31) | 222 (29) |
| ≥10 | 22 (15) | 82 (11) |
| Digital rectal examination | ||
| Normal | 89 (61) | 643 (83) |
| Abnormal | 57 (39) | 129 (17) |
| Cancer length (mm) | ||
| 0–5 | 6 (4) | 201 (26) |
| 5–10 | 16 (11) | 175 (23) |
| 10–20 | 41 (28) | 189 (24) |
| 20–40 | 47 (32) | 152 (20) |
| >40 | 36 (25) | 55 (7) |
| ISUP | ||
| 1 | 13 (9) | 208 (27) |
| 2 | 78 (53) | 373 (48) |
| 3 | 34 (23) | 106 (14) |
| 4–5 | 21 (14) | 85 (11) |
| Number of PNI positive cores | ||
| 0 | 0 (0) | 772 (100) |
| 1 | 90 (62) | 0 (0) |
| 2 | 31 (21) | 0 (0) |
| 3 | 11 (8) | 0 (0) |
| 4 or more | 14 (10) | 0 (0) |
| Pathological stage | ||
| T2 | 73 (50) | 584 (76) |
| T3a | 62 (42) | 161 (21) |
| T3b/T4 | 11 (8) | 27 (3) |
| Surgical margin | ||
| Negative | 113 (77) | 603 (78) |
| Positive | 33 (23) | 169 (22) |
| Events | 31 | 82 |
| Person-years | 555 | 3143 |
All variables were from the biopsy except pathological stage and surgical margin. Pathological stage was confined to the prostate (pT2), extraprostatic growth (pT3a) or seminal vesicle invasion (pT3b); there was only one case of pT4.
PNI, perineural invasion.