ANC correlation in samples from patients with haematological malignancies
Haematological malignancy type | Total cases, % | ANC confirmed by smear review, % | Manual differential performed, % | Automated and manual differential correlation characteristics | |
R2 | Slope | ||||
Lymphoma | 196 (34) | 35 (6) | 161 (28) | 0.97 | 0.85 |
Leukaemia | 189 (33) | 18 (3) | 171 (30) | 0.95 | 0.99 |
Plasma cell dyscrasia* | 59 (10) | 21 (3) | 38 (6) | 0.97 | 0.84 |
BMT | 56 (10) | 15 (3) | 41 (7) | 0.97 | 0.85 |
MDS | 38 (6) | 13 (2) | 25 (4) | 0.99 | 0.89 |
MPN | 25 (4) | 6 (1) | 19 (3) | 0.99 | 0.94 |
Non-malignant haematological disorders | 7 (1) | 0 (0) | 7 (100) | 0.98 | 0.88 |
*Plasma cell dyscrasias include multiple myeloma and plasmacytoma.
ANC, absolute neutrophil count; BMT, bone marrow transplant; MDS, myelodysplastic syndrome; MPN, myeloproliferative neoplasm.