Table 1

Demographic and selected clinical laboratory predictor variables on admission for evaluation cohort

VariableSurvivors (n=278)Non-survivors (n=113)P value
Frequency (n (%))% missingFrequency (n (%))% missing
Gender0.00.0
 Male141 (50.7)64 (56.6)0.316†
 Female137 (49.3)49 (44.4)
WIMD*2.50.90.228†
 Quartile 1 (<246)65 (23.4)29 (25.6)
 Quartile 2 (246 – 871)61 (21.9)35 (31.0)
 Quartile 3 (872–1672)73 (26.3)23 (20.4)
 Quartile 4 (>1672)72 (25.9)25 (22.1)
Median (IQR)Median (IQR)
Age, years63.5 (51.3–77.8)0.081.0 (71.0–88.0)0.0<0.0001
’Core’ test componentMedian (IQR)
 Albumin, g/L33.0 (29.0–36.0)3.229.0 (26.0–32.0)1.8<0.0001
 Alkaline phosphatase U/L80.0 (63.0–111.5)0.0100.0 (76.0–133.5)0.00.0006
 Alanine transaminase U/L27.0 (17.0–46.0)0.023.0 (14.0–32.0)0.00.256
 Bilirubin μmol/L10.0 (7.0–15.0)0.012.0 (8.0–17.0)0.00.0018
 C reactive protein, mg/L70.5 (21.0–131.8)0.098.0 (55.75–164. 8)2.60.005
 Creatinine, µmol/L82.0 (66.0–105.0)0.4111.0 (79.0–192.0)0.0<0.0001
 Estimated glomerular filtration rate
 (eGFR) mL/min/1.73 m2
75.0 (55.0–89.0)0.051.0 (25.0–74.0)0.0<0.0001
 Globulin g/L38.0 (34.0–42.0)0.140.0 (36.0–45.75)0.10.0161
 Haemoglobin g/L135.0 (122.0–149.0)0.0135.0 (122.0–149.0)0.00.036
 Lymphocyte count ×109/L1.0 (0.7–1.4)0.00.9 (0.6–1.2)0.00.961
 Neutrophil count ×109/L5.4 (3.7–8.0)0.07.3 (4.6–9.8)0.00.017
 Neutrophil:lymphocyte ratio5.25 (3.3–9.8)0.48.11 (4.3–14.5)0.90.011
 Platelet count ×109/L234.0 (183.8–294.5)0.0216.0 (160.0–285.0)0.00.210
 Potassium mmol/L3.9 (3.6–4.3)0.04.1 (3.7–4.6)0.00.0006
 Protein g/L71.0 (67.0–76.0)0.170.0 (65.0–74.0)0.10.04
 Sodium mmol/L137.0 (134.0–139.0)0.0138.0 (134.0–141.0)0.0<0.0001
 Urea mmol/L5.7 (4.0–8.5)0.410.2 (7.2–16.2)0.0<0.0001
 White cell count ×109/L7.35 (5.3–9.9)0.09.0 (6.4–12.3)0.00.016
’Extended’ test component
 Ferritin μg/L325.0 (125.0–828.0)57.9482.0 (245.5–993.5)54.90.395
 High-sensitivity D-dimer μg/L926.5 (587.75–1750.0)28.11497.0 (929.0–3885.0)30.10.0003
 High-sensitivity troponin I ng/L7.0 (3.0–23.0)24.835.5 (15.75–117.0)22.1<0.0001
 Lactate dehydrogenase U/L349.5 (270.3–549.8)53.2383.5 (290.5–501.3)54.00.999
 Procalcitonin μg/L0.14 (0.1–0.4)41.40.31 (0.1–0.9)38.90.019
  • Variables captured in the summarised cohort of community-acquired PCR-confirmed COVID-19 cases admitted through the Emergency Department between 17 March 2020 and 30 June 2020. Summary statistics are given as the median and range for continuous variables and absolute counts for discrete variables. *Welsh index of multiple deprivation, WIMD, is ranked from 1 (most deprived) to 1909 (least deprived) and presented as frequencies within each quartile. †Fischer’s exact test.