Table 2

HScore parameters and bone marrow pathological findings

PatientBasal IS*HepatomegalySplenomegalyMaximum body T (°C)Lowest Hb*Lowest WBC†Lowest
platelets†
Maximum ferritin‡Maximum triglycerid§Lowest fibrinogen¶Max GOT**Haemophagocytosis in BMN° histiocytes††Haemophagocyt images per HPFHScore points‡‡% Probability
HScore
1NoNoNo<38.4°C8.86.448.427004.8170215Yes60 (12%)1.3207/33792
2NoNoNo<38.4°C10.48.48177NANA53048Yes50 (10%)2.354/2230.09
3NoNoNo>38.4°C<39.4°C7.32.9671.919886.45180101Yes36 (7%)1.9196/33785
4NoNoNo>38.4°C<39.4°C7.92.417.6NANA140116Yes50 (10%)1.4151/22326.3
5NoNoNo<38.4°C72.354114364.1616074Yes67 (13%)3.2182/33770.97
6NoNoNo>38.4°C<39.4°C8.14.69532163NA10082Yes55 (11%)3.2186/27375.8
7NoNoNo>38.4°C<39.4°C8.72.8106795NA12054Yes55 (11%)1.4151/27326.3
8YesNoNo>38.4°C<39.4°C10.12.8170NANA36022Yes50 (10%)1.386/2230.63
9NoNoNo>38.4°C<39.4°C7.64.0760.916895.116067Yes62 (12%)1.7215/33794.97
10NoNoNo≥39.4°C8.34.0279.75169.31140124Yes50 (10%)2.2212/33794
11NoNoNo>38.4°C<39.4°C7.68.712014541.236058Yes59 (12%)1.887/3370.67
12NoNoNo≥39.4°C12.510.431.67140.4916087Yes60 (12%)4.7133/33710.4
13YesYesYes≥39.4°C6.50.0182494NA29085Yes45 (9%)0.6239/27398.8
14NoYesNo≥39.4°C6.32.7930.86664.24280124Yes34 (7%)1.1224/33797.06
15NoYesNo<38.4°C8.1580.317593.2811057Yes43 (9%)1.6185/33774.64
16NoYesNo≥39.4°C63.936069005.12100129Yes40 (8%)0.5304/33799.97
  • *g/dL.

  • †103/µL.

  • ‡ng/mL.

  • §mmol/L.

  • ¶mg/dL.

  • **U/L.

  • ††Nº histiocytes per 500 nucleated cells.

  • ‡‡Score points/ maximal points for this patient with his/her available parameters.

  • BM, bone marrow; GOT, glutamic oxaloacetic transaminase; Hb, haemoglobin; HPF, high power field; IS, immunosuppression; NA, not available; WBC, white cell count.