Table 1

Neoplasms associated with Lynch syndrome4 13 30

Cancer typeNotes
 Colorectal carcinoma (CRC)*Accounts for 3%–5% of all CRC
 Gastric adenocarcinoma
 Small intestinal adenocarcinoma
 Pancreatic adenocarcinoma
 Endometrial carcinoma*Accounts for 2%–3% of all endometrial cancers
 Ovarian carcinoma
Other sites
 Urinary tract carcinoma (transitional cell)
 Prostatic carcinoma
 Cutaneous sebaceous tumours†Muir-Torre syndrome
 Adrenocortical carcinoma
 Germ cell tumours
  • *CRC and endometrial carcinoma are the two neoplasms most commonly associated with Lynch syndrome.

  • †There is also an increased risk of development of keratoacanthoma.