Type specific concordance between Papilloplex and GP5+/6+PCR-EIA/Luminex
HPV type | P+/G+ | P+/G- | P-/G+ | P-/G- | Concordance | K |
14hrHPV* | 343 | 48 | 43 | 766 | 92.4% | 0.827 |
14hrHPV† | 349 | 42 | 52 | 752 | 92.1% | 0.823 |
HPV16 | 78 | 0 | 22 | 1095 | 98.2% | 0.867 |
HPV18 | 23 | 0 | 25 | 1147 | 97.9% | 0.639 |
HPV31 | 44 | 3 | 6 | 1142 | 99.3% | 0.903 |
HPV33 | 24 | 1 | 10 | 1160 | 99.1% | 0.809 |
HPV35 | 10 | 1 | 11 | 1173 | 99.0% | 0.620 |
HPV39 | 16 | 0 | 0 | 1179 | 100.0% | 1.000 |
HPV45 | 36 | 11 | 6 | 1142 | 98.6% | 0.802 |
HPV51 | 23 | 10 | 14 | 1148 | 98.0% | 0.647 |
HPV52 | 30 | 15 | 2 | 1148 | 98.6% | 0.772 |
HPV56 | 28 | 1 | 15 | 1151 | 98.7% | 0.771 |
HPV58 | 20 | 9 | 1 | 1165 | 99.1% | 0.796 |
HPV59 | 9 | 5 | 12 | 1169 | 98.6% | 0.507 |
HPV66 | 36 | 10 | 6 | 1143 | 98.7% | 0.811 |
HPV68 | 12 | 8 | 0 | 1175 | 99.3% | 0.747 |
‘P’=Papilloplex HR-HPV test and ‘G=GP5+/6+-Luminex’. Colour legend (adapted from Landis and Koch for the levels of agreement (31,12)): dark green (1.00 ≥κ≥0.80): excellent; light green (0.80≥κ>0.60): good; yellow (0.60≥κ>0.40): moderate; orange (0.40≥κ>0.20): fair; red (0.20≥κ>0.00): poor.
*Concordance between Papilloplex and GP5+/6+PCR EIA for presence or absence of the 14 hrHPV types.
†Concordance between Papilloplex and GP5+/6+PCR-LMNX.
EIA, enzyme immunoassay; hrHPV, high-risk human papillomavirus.