Table 2

Haemoglobin fractions, β-globin genotypes and clinical phenotypes in a family affected with Hb D and β+-thalassemia trait

PatientGenderHb A (%)Hb A 2 (%)Hb F (%)Hb D (%)β-globin genotypeClinical phenotype
1M95.14.30.6Nc.92+5G>C/normalβ-thalassemia trait
2F60.82.3<0.536.9Normal/c.364G>CHb D-carrier
3F97.52.5<0.5NNormal/normalNormal
4F58.42.70.538.9Normal/c.364G>C*Hb D-carrier
5M97.52.5<0.5NNormal/normalNormal
6M3.54.7<0.591.8c.92+5G>C/c.364G>C*Hb D/β-thalassemia trait
7F964<0.5Nc.92+5G>C/normal*β-thalassemia trait
8M96.92.80.3NNormal/normalNormal
9F97.02.60.4NNormal/normalNormal
  • Hb fractions on the Minicap Flex Piercing CZE system, β-globin genotypes and clinical phenotypes are presented. N denotes absent.

  • *Extrapolated genotype.

  • CZE, capillary zone electrophoresis.