Haematological and coagulation and biochemistry parameters in patients with and without COVID-19 reactive lymphocytes (COVID-19 RL)
| Parameter | Patients with COVID-19 RL | Patients without COVID-19 RL | P | |||
| Mean | SD | Mean | SD | |||
| Haematological | RBC (1012/L) | 4.54 | 0.73 | 3.27 | 0.82 | <0.001* |
| Haemoglobin (g/L) | 136 | 22 | 101 | 25 | <0.001* | |
| Haematocrit (L/L) | 0.405 | 0.060 | 0.318 | 0.080 | 0.001* | |
| MCV (fL) | 89.6 | 4.9 | 97.2 | 5.4 | <0.001* | |
| MCH (pg) | 30.1 | 1.5 | 31.0 | 1.4 | 0.058 | |
| MCHC (g/L) | 335.7 | 8.1 | 319.4 | 9.2 | <0.001* | |
| Platelets (109/L) | 268 | 148 | 202 | 121 | 0.090 | |
| MPV (fL) | 8.3 | 1.0 | 9.9 | 2.1 | 0.007* | |
| MPC (gL) | 25.0 | 2.3 | 23.9 | 2.0 | 0.149 | |
| MPM (pg) | 2.75 | 3.36 | 2.09 | 0.29 | 0.326 | |
| WBC (109/L) | 5.3 | 4.4 | 9.8 | 8.8 | 0.235 | |
| Neutrophils (109/L) | 2.9 | 3.4 | 8.1 | 7.9 | 0.044* | |
| Lymphocytes (109/L) | 1.6 | 1.5 | 0.8 | 0.7 | 0.012* | |
| NLR | 2.2 | 1.6 | 19.5 | 32.2 | <0.001* | |
| Monocytes (109/L) | 0.39 | 0.25 | 0.54 | 0.53 | 0.620 | |
| Eosinophils (109/L) | 0.20 | 0.43 | 0.07 | 0.10 | 0.127 | |
| Basophils (109/L) | 0.02 | 0.04 | 0.02 | 0.05 | 0.961 | |
| LUC (109/L) | 0.16 | 0.18 | 0.18 | 0.24 | 0.702 | |
| PMN (%) | 55.5 | 13.2 | 76.5 | 13.1 | <0.001* | |
| MN (%) | 43.4 | 13.1 | 22.7 | 13.0 | <0.001* | |
| PMN/MN ratio | 1.5 | 0.8 | 4.7 | 2.8 | <0.001* | |
| RL (109/L) | 0.21 | 0.36 | 0.00 | 0.00 | <0.001* | |
| Coagulation and biochemistry | PT (s) | 12.8 | 1.3 | 14.2 | 3.3 | 0.255 |
| D-dimer (μg/L) | 856 | 572 | 2900 | 1744 | <0.001* | |
| CRP (mg/L) | 24 | 25 | 45 | 50 | 0.242 | |
| ASAT (U/L) | 58 | 51 | 44 | 36 | 0.349 | |
| ALAT (U/L) | 77 | 71 | 46 | 34 | 0.272 | |
| GGT (U/L) | 115 | 209 | 111 | 97 | 0.221 | |
| ALP (U/L) | 90 | 81 | 108 | 53 | 0.021* | |
| Total bilirubin (mmol/L) | 0.011 | 0.006 | 0.016 | 0.023 | 1.000 | |
| Direct bilirubin (mmol/L) | 0.004 | 0.003 | 0.009 | 0.017 | 0.322 | |
| LDH (U/L) | 277 | 97 | 383 | 172 | 0.076 | |
| Ferritin (nmol/L) | 2.4 | 1.5 | 2.3 | 2.7 | 0.346 | |
| Procalcitonin (μg/L) | 0.06 | 0.03 | 0.58 | 1.13 | 0.023* | |
| BUN (mmol/L) | 6.9 | 2.7 | 18.7 | 11 | 0.032* | |
| Creatinine (mmol/L) | 0.08 | 0.02 | 0.15 | 0.11 | 0.067 | |
| GFR (mL/min/1.73 m2) | 85.11 | 12.4 | 50.92 | 31.69 | 0.001* | |
| Total protein (g/L) | 662 | 71 | 541 | 65 | <0.001* | |
| Albumin (g/L) | 390 | 48 | 315 | 39 | <0.001* | |
*Significant differences.
ALAT, alanine aminotransferase; ALP, alkaline phosphatase; ASAT, aspartate aminotransferase; BUN, blood urea nitrogen; CRP, C-reactive protein; GFR, glomerular filtration rate; GGT, gamma-glutamyl transferase; LDH, lactate dehydrogenase; LUC, large unstained cells; MCH, mean corpuscular haemoglobin; MCHC, mean corpuscular haemoglobin concentration; MCV, mean corpuscular volume; MN, mononuclear leucocytes; MPC, mean platelet component; MPM, mean platelet mass; MPV, mean platelet volume; NLR, neutrophil/lymphocyte ratio; PMN, polymorphonuclear leucocytes; PT, prothrombin time; RBC, red blood cells; WBC, white blood cells.