Table 2

Logistic regression model 1 for the testing rate

ALKEGFRPD-L1ROS1
OR (95% CI)P valueOR (95% CI)P valueOR (95% CI)P valueOR (95% CI)P value
Sample type* (ref. biopsy)
 Cell block0.84 (0.62 to 1.17)0.2911.41 (0.93 to 2.23)0.1210.44 (0.35 to 0.56)<0.0010.77 (0.61 to 0.97)0.026
 FNA0.16 (0.12 to 0.22)<0.0012.89 (1.44 to 6.88)0.0070.03 (0.02 to 0.05)<0.0010.24 (0.17 to 0.33)<0.001
 Surgical piece0.66 (0.52 to 0.85)0.0011.10 (0.80 to 1.55)0.5680.62 (0.51 to 0.75)<0.0010.97 (0.79 to 1.18)0.726
 Others0.20 (0.15 to 0.26)<0.0012.2 (1.28 to 4.10)0.0080.17 (0.13 to 0.22)<0.0010.33 (0.26 to 0.44)<0.001
NSCLC-NOS (ref. adenocarcinoma)0.93 (0.68 to 1.29)0.6661.06 (0.68 to 1.72)0.8061.31 (0.99 to 1.75)0.0620.87 (0.68 to 1.13)0.296
Hosmer-Lemeshow, p value >0.999 0.957 0.968 0.998
AUROC (95% CI) 0.65 (0.62 to 0.67) 0.559 (0.530 to 0.589) 0.673 (0.655 to 0.691) 0.588 (0.569 to 0.606)
  • The results of the Hosmer-Lemeshow test and the AUROC are in italics to differentiate them from the ORs.

  • *Category ‘others’ includes blood samples.

  • ALK, anaplastic lymphoma kinase; AUROC, area under receiver operating characteristic curve; EGFR, epidermal growth factor receptor; FNA, fine-needle aspiration; NSCLC-NOS, non-small cell lung cancer–not otherwise specified; PD-L1, programmed death ligand-1; ref., reference; ROS1, c-ros oncogene 1.