Table 4

Logistic regression model 1 for the positivity rate

ALKEGFRPD-L1
OR (95% CI)P valueOR (95% CI)P valueOR (95% CI)P value
Sample type* (ref. biopsy)
 Cell block0.77 (0.31 to 1.60)0.5130.95 (0.66 to 1.36)0.8021.00 (0.72 to 1.37)0.984
 FNA1.72 (0.59 to 4.04)0.2611.20 (0.76 to 1.84)0.4170.86 (0.28 to 2.60)0.785
 Surgical piece1.13 (0.62 to 1.96)0.6820.94 (0.69 to 1.25)0.6610.80 (0.63 to 1.03)0.081
Blood1.54 (0.85 to 2.65)0.134
 Others1.48 (0.60 to 3.12)0.3411.47 (0.96 to 2.19)0.0681.17 (0.73 to 1.88)0.515
NSCLC-NOS (ref. adenocarcinoma)0.85 (0.33 to 1.83)0.7070.16 (0.07 to 0.33)<0.0011.20 (0.87 to 1.66)0.256
Hosmer-Lemeshow, p value 0.997 0.995 0.997
AUROC (95% CI) 0.543 (0.486 to 0,601) 0.565 (0.538 to 0.592) 0.526 (0.503 to 0.549)
  • The results of the Hosmer-Lemeshow test and the AUROC are in italics to differentiate them from the ORs.

  • *Category ‘others’ includes blood samples for ALK and PD-L1 models.

  • ALK, anaplastic lymphoma kinase; AUROC, area under receiver operating characteristic curve; EGFR, epidermal growth factor receptor; FNA, fine-needle aspiration; NSCLC-NOS, non-small cell lung cancer–not otherwise specified; PD-L1, programmed death ligand-1; ref., reference.