Frequency of crypt-associated anomalies found in H&E-stained sections of 100 cases with ulcerative colitis, 50 cases with infectious colitis and 29 cases with ulcerative colitis in remission
Crypt-associated anomalies | Ulcerative colitis (n=100) | Infectious colitis (n=50) | Ulcerative colitis in remission (n=29) |
Extensive crypt eosinophilia | 58 | 10 | 0 |
Intracryptal epithelial hyperplasia | 23 | 7 | 1 |
Mean | 0.23 | 0.14 | 0.03 |
Range | 0–3 | 0–2 | |
Intracryptal epithelial budding | 191 | 28 | 5 |
Mean | 1.9 | 0.56 | 0.17 |
Range | 0–11 | 0–4 | 0–1 |
Intracryptal supernumerary crypts | 41 | 19 | 2 |
Mean | 0.4 | 0.38 | 0.07 |
Range | 0–13 | 0–7 | |
Intraluminal epithelial bridges | 5 | 2 | 0 |
Mean | 0.05 | 0.04 | |
Range | 0–1 | ||
Crypt rings in rows | 12 | 3 | 0 |
Mean | 0.12 | 0.06 | |
Range | 0–1 | 0–1 | |
Off-centre epithelial budding | 17 | 3 | 0 |
Mean | 0.17 | 0.06 | |
Range | 0–6 | 0–1 | |
Severe mucosal inflammation (%) | 52 (52) | 13 (26) | 0 |