Table 1

Frequency of crypt-associated anomalies found in H&E-stained sections of 100 cases with ulcerative colitis, 50 cases with infectious colitis and 29 cases with ulcerative colitis in remission

Crypt-associated anomaliesUlcerative colitis
(n=100)
Infectious colitis
(n=50)
Ulcerative colitis in remission
(n=29)
Extensive crypt eosinophilia58100
Intracryptal epithelial hyperplasia2371
 Mean0.230.140.03
 Range0–30–2
Intracryptal epithelial budding191285
 Mean1.90.560.17
 Range0–110–40–1
Intracryptal supernumerary crypts41192
 Mean0.40.380.07
 Range0–130–7
Intraluminal epithelial bridges520
 Mean0.050.04
 Range0–1
Crypt rings in rows1230
 Mean0.120.06
 Range0–10–1
Off-centre epithelial budding1730
 Mean0.170.06
 Range0–60–1
Severe mucosal inflammation (%)52 (52)13 (26)0