Primary AI | |
Autoimmune | Isolated, autoimmune polyendocrinopathy syndrome types 1 and 2 |
Infection | Tuberculosis, HIV, fungal, viral |
Others | Bilateral adrenal haemorrhage, adrenal metastasis, adrenal infiltration, bilateral adrenalectomy, drug induced |
Genetic | Adrenoleukodystrophy, congenital adrenal hyperplasia, adrenal hypoplasia congenita, adrenocorticotropic hormone, insensitivity syndromes |
Secondary AI | |
Space occupying lesions/trauma/surgery | Pituitary tumours, trauma, surgery, irradiation |
Infection or infiltration affecting anterior pituitary, pituitary apoplexy, Sheehan’s syndrome, drugs | |
Tertiary AI | |
Space occupying lesions/trauma/surgery | Hypothalamic tumours, trauma, surgery, irradiation |
Drug induced | Glucocorticoid, piates |
AI, adrenal insufficiency.