Summarised histopathological and clinical information
| TERT promoter mutated and TERT mRNA expressing cases (n=10) | |
| Median age at surgery (range) | 71.5 (38–91) |
| Sex, female:male | 6:4 |
| Median tumour size in mm (range) | 45 (15–100) |
| Histological type | wiFTC (n=6), FT-UMP (n=2), miFTC (n=1), HCC (n=1) |
| Median Ki-67 index (range) | 7.5 (1.3–12) |
| Distant metastases/local recurrences | Lung met (n=2), bone met (n=2), local recurrence (n=1) |
| Average age of tissue blocks | 2248 days |
| TERT promoter wildtype and TERT mRNA negative cases (n=16) | |
| Median age at surgery (range) | 50 (11–71) |
| Sex, female:male ratio | 15:1 |
| Median tumour size in mm (range) | 42 (20–58) |
| Histological type | wiFTC (n=9), eaiFTC (n=2), miFTC (n=5) |
| Median Ki-67 index (range) | 4.25 (1–12.5) |
| Distant metastases/local recurrences | None reported |
| Average age of tissue blocks | 2234 days |
eaiFTC, encapsulated angioinvasive follicular thyroid carcinoma; FT-UMP, follicular thyroid tumour of uncertain malignant potential; HCC, Hürthle cell carcinoma; miFTC, minimally invasive follicular thyroid carcinoma; wiFTC, widely invasive follicular thyroid carcinoma.