Sample number | Diagnosis | TERT promoter* | TERT expression (qRT-PCR)* | In situ hybridisation | |
TERT1 | TERT2 | ||||
1 | wiFTC | Mutated | Yes | Focal | Neg |
2 | wiFTC | Mutated | Yes | Focal | Focal |
3 | wiFTC | Mutated | Yes | Neg | Neg |
4 | wiFTC | Mutated | Yes | Focal | Focal |
5 | wiFTC | Mutated | Yes | Focal | Focal |
6 | miFTC | Mutated | Yes | Focal | Focal |
7 | wiFTC | Mutated | Yes | Neg | Neg |
8 | FT-UMP | Mutated | Yes | Neg | Focal |
9 | FT-UMP | Mutated | Yes | Neg | Focal |
10 | HCC | Mutated | Yes | Focal | Focal |
11 | miFTC | Wildtype | None | Neg | Neg |
12 | miFTC | Wildtype | None | Neg | Neg |
13 | eaiFTC | Wildtype | None | Neg | Neg |
14 | miFTC | Wildtype | None | Neg | Neg |
15 | wiFTC | Wildtype | None | Neg | Neg |
16 | wiFTC | Wildtype | None | Neg | Neg |
17 | miFTC | Wildtype | None | Neg | Neg |
18 | wiFTC | Wildtype | None | Neg | Neg |
19 | wiFTC | Wildtype | None | Neg | Neg |
20 | miFTC | Wildtype | None | Neg | Neg |
21 | wiFTC | Wildtype | None | Neg | Neg |
22 | wiFTC | Wildtype | None | Neg | Neg |
23 | wiFTC | Wildtype | None | Neg | Neg |
24 | wiFTC | Wildtype | None | Neg | Neg |
25 | wiFTC | Wildtype | None | Neg | Neg |
26 | eaiFTC | Wildtype | None | Neg | Neg |
*Retrieved from Paulsson et al. 9
eaiFTC, encapsulated angioinvasive follicular thyroid carcinoma; FT-UMP, follicular thyroid tumour of uncertain malignant potential; HCC, HÃ¼rthle cell carcinoma; miFTC, minimally invasive follicular thyroid carcinoma; Neg, negative; qRT-PCR, quantitative real-time PCR; wiFTC, widely invasive follicular thyroid carcinoma.