Table 1

Associations between PD-L1 expression and clinicopathological characteristics

SubgroupNT-PD-L1 (5% cut-off value)I-PD-L1 (1% cut-off value)
NegativePositiveP valueNegativePositiveP value
Overall9656405046
Gender
Female6 (5.3)3 (3.8)0.8593 (4.7)6 (4.3)0.405
Male50 (50.8)37 (36.3)47 (45.3)40 (41.7)
Age (years)
≤7526 (27.4)21 (19.6)0.55723 (24.5)24 (22.5)0.545
>7530 (28.6)19 (20.4)27 (25.5)22 (23.5)
Tumour differentiation
Single differentiation51 (49.0)33 (35.0)0.21141 (43.8)43 (40.3)0.165
With other components5 (7.0)7 (5.0)9 (6.3)3 (5.8)
Tumour depth
T110 (8.8)5 (6.3)0.1697 (7.8)8 (7.2)0.865
T240 (37.9)25 (27.1)34 (33.9)31 (31.1)
T3/46 (9.3)10 (6.7)9 (8.3)7 (7.7)
LN metastasis
Absent50 (48.4)33 (34.6)0.33842 (43.2)41 (39.8)0.463
Present6 (7.6)7 (5.4)8 (6.8)5 (6.2)
TNM stage
I–II46 (41.4)25 (29.6)0.03136 (37.0)35 (34.0)0.649
III–IV10 (14.6)15 (10.4)14 (13.0)11 (12.0)
TILs
Absent31 (22.8)8 (16.3)0.00133 (20.3)6 (18.7)<0.001
Present25 (33.3)32 (23.8)17 (29.7)40 (27.3)
T-PD-L1 (5% cut-off value)
Negative34 (29.2)22 (26.8)0.045
Positive16 (20.8)24 (19.2)
I-PD-L1 (1% cut-off value)
Negative34 (29.2)16 (20.8)0.045
Positive22 (26.8)24 (19.2)
  • TILs, tumour infiltrating lymphocytes.