Table 2

Cells secrete basement membrane (BM) components

ComponentsSecreting cellsSpecial features
Collagen IVMyoepithelial cells98
Fibroblasts99
Endothelial cells100
Pericytes100 		Network101
Lamininsβ1, γ1 → epithelial cells
α1 → epithelial cells
α2 and β3 → fibroblasts
γ2 → epithelial cell and Mesenchymal stem
cells (MSC)102
Tumour cells9 103 104 		Network glycoprotein
11 isoforms105
PerlecanEpithelium102 106
Endothelium14
Mesenchymal cells14 		Heparan sulfate proteoglycan107
Agrinα-Smooth muscle actin+ve (SMA+ve) cells108
Motor neurons109
Myofibroblasts108 		Proteoglycan101
Nidogen (entactin)Mesenchymal cells110 111
Fibroblasts102
BM-40/SPARCEndothelium14 112 Ca binding101
Fibulin 1Epithelium113 114
Mesenchymal cells113 114
Tumour cells115 116 		Ca binding
Glycoprotein113
Fibulin 2Epithelium113 114
Fibroblasts117
Mesenchymal cells113 114 		Ca binding
Glycoprotein113
Collagen VIIEpithelial cells118
Fibroblasts99 		Fibrillar99

  • SPARC, secreted protein acidic and rich in cysteine.