Table 4

Immunohistochemistry result for H3F3 K36M mutant antibody in 185 chondroblastomas and 670 other primary bone lesions

DiagnosisNo of positive cases/no of cases tested
Chondroblastoma non-decalcified136/136
Chondroblastoma decalcified in HCl27/31
Chondroblastoma decalcified in EDTA18/18
Giant cell-rich bone lesions0/419
 Giant cell tumour of bone0/233
 Aneurysmal bone cyst0/39
 Non-ossifying fibroma0/42
 Tenosynovial giant cell tumour0/89
 Osteoblastoma/osteoid osteoma0/9
 Phosphaturic mesenchymal tumour0/4
 Brown tumour (hyperparathyroidism)0/3
 Clear cell chondrosarcoma0/24
 Atypical cartiladinous tumour/chondrosarcoma, grade 10/7
 Chondrosarcoma grade 2 and 30/17
 Mesenchymal chondrosarcoma0/3
 Dedifferentiated chondrosarcoma0/1
 Chondromyxoid fibroma0/9
 Fibrocartilaginous mesenchymoma0/1
 Chondroblastic osteosarcoma0/28
Other lesions of bone0/161
 Osteosarcoma (other than chondroblastic osteosarcoma)0/116
 Fibrous dysplasia0/19
 Langerhans cell histiocytosis0/5
 Poorly differentiated chordoma0/1
 Simple bone cyst0/19
  • HCl, hydrochloric acid.