Detection of SARS-CoV-2 T-cell responses to S-protein and N-protein and antibody responses to S-proteins (EUROIMMUN) and N-proteins (Roche Elecsys)
SARS-CoV-2 antibody assay | Negative group (n=110) | Positive group (n=52) | P value Antibody results | P value T-cell results | ||
Positive antibody results | Positive T-cell response | Positive antibody results | Positive T-cell response | |||
SARS-CoV-2 N-protein target | 8 (7.27%) | 61 (55.45%) | 41 (78.84%) | 42 (80.77%) | <0.001 | 0.001 |
SARS-CoV-2 S-protein target | 8 (7.27%) | 53 (48.18%) | 40 (76.92%) | 38 (73.08%) | <0.001 | 0.002 |
Any SARS-CoV-2 protein target | 8 (7.27%) | 68 (61.82%) | 41 (78.84%) | 42 (80.77%) | <0.001 | 0.011 |