Table 4

Multivariate logistic regression analysis to assess the independent significance of various clinicopathological parameters for progression to advanced neoplasia

Clinicopathological parametersOR (95% CI)P valueAdjusted
OR (95% CI)
P value
Gender: male versus female3.7
(1.9 to 6.8)
<0.0012.9
(1.3 to 6.3)
0.008
Age: ≤55 years vs >55 years2.7
(1.6 to 4.7)
<0.0013.2
(1.6 to 6.6)
0.001
Endoscopic length of BE:
Long segment versus short segment
5.2
(3.0 to 9.1)
<0.0015.5
(2.9 to 10.4)
<0.001
3+p53 positive columnar cells
<10 cells vs ≥10 cells
8.9
(4.2 to 18.7)
<0.0013.4
(1.2 to 9.8)
0.023
Presence of 3+p53 positive glands
≥1 gland versus negative
13.3
(4.5 to 38.9)
<0.0016.3
(1.5 to 26.7)
0.013
  • BE, Barrett’s oesophagus.