Table 1

Clinical features of the four cases with NTRK gene alterations in gastric cancer

Case IDSexLocationSize (cm)LaurenTNMNTRK gene alterationFollow-up
1MAntrum5.0IntestinalT3, N3b, M0NTRK1 AmplificationLTF
2MAntrum3.5IntestinalT3, N1, M0NTRK3 AmplificationDOD (63 months)
3MAntrum5.6MixedT3, N3b, M1TPM3-NTRK1 fusionDOD (10 months)
4MAntrum5.2IntestinalT3, N2, M0NTRK2-SMCHD1 fusionNED (24 months)
  • DOD, dead of disease; LTF, lost to follow-up; M, male; NED, no evidence of disease.