Table 3

Marker expression in HFE and non-HFE groups

ProcessNon-HFE, n /N (%)HFE, n/N (%)P value
EpCAMCSC2/11 (18)8/11 (72)0.030
SALL4CSC2/11 (18)6/11 (55)0.183
EpCAM/SALL4 coexpressionCSC0/11 (0)5/11 (45)0.035
CD44CSC and EMT7/11 (64)9/11 (81)0.635
VimentinEMT1/11 (9)6/11 (55)0.063
β-cateninEMT10/11 (91)6/11 (55)0.149
E-cadherin*EMT8/11 (72)8/11 (72)1.000
CK18*EMT3/11 (27)8/11 (73)0.086
  • *Expression ≥5 on a scale of 0–9.

  • CSC, cancer stem cells; EMT, epithelial–mesenchymal transition; EpCAM, epithelial cell adhesion molecule; HFE, haemochromatosis; SALL4, spalt-like transcription factor 4.