molecular

Expression of programmed death-ligand 1 protein in pulmonary squamous cell carcinoma correlates with tumour necrosis but not with tumour differentiation
Vladimír Tancoš, Anna Farkašová, Zuzana Kviatkovská, Marián Grendár, Alena Líšková, Zdenko Huťka, Lukáš Plank

Journal of Clinical Pathology Jun 2022, 75 (6) 373-378; DOI: 10.1136/jclinpath-2020-207171
Does histological assessment accurately distinguish separate primary lung adenocarcinomas from intrapulmonary metastases? A study of paired resected lung nodules in 32 patients using a routine next-generation sequencing panel for driver mutations
Frido K Bruehl, Erika E Doxtader, Yu-Wei Cheng, Daniel H Farkas, Carol Farver, Sanjay Mukhopadhyay

Journal of Clinical Pathology Jun 2022, 75 (6) 390-396; DOI: 10.1136/jclinpath-2021-207421
TargetPlex FFPE-Direct DNA Library Preparation Kit for SiRe NGS panel: an international performance evaluation study
Umberto Malapelle, Francesco Pepe, Pasquale Pisapia, Roberta Sgariglia, Mariantonia Nacchio, Massimo Barberis, Michel Bilh, Lukas Bubendorf, Reinhard Büttner, Daniela Cabibi, Marta Castiglia, Carlos E De Andrea, Dario de Biase, Catherine I Dumur, Gabriella Fontanini, Javier Freire, Valerio Gristina, Paul Hofman, Marius Ilie, Maria Dolores Lozano, Sabine Merkelbach-Bruse, Roberto Pappesch, Natalie Pelusi, Gianluca Roma, Antonio Russo, Spasenija Savic, Janna Siemanowski, Giovanni Tallini, Verena Tischler, Sara Vander Borght, Birgit Weynand, Tom Xu, Giancarlo Troncone

Journal of Clinical Pathology Jun 2022, 75 (6) 416-421; DOI: 10.1136/jclinpath-2021-207450
p63 expression is associated with high histological grade, aberrant p53 expression and TP53 mutation in HER2-positive breast carcinoma
Shuangping Guo, Yingmei Wang, Joseph Rohr, Li Shang, Jing Ma

Journal of Clinical Pathology Oct 2021, 74 (10) 641-645; DOI: 10.1136/jclinpath-2020-206643
Nuclear-specific accumulation of telomerase reverse transcriptase (TERT) mRNA in TERT promoter mutated follicular thyroid tumours visualised by in situ hybridisation: a possible clinical screening tool?
L Samuel Hellgren, Ann Olsson, Ann Kaufeldt, Johan O Paulsson, Martin Hysek, Adam Stenman, Jan Zedenius, Catharina Larsson, Anders Höög, C Christofer Juhlin

Journal of Clinical Pathology Oct 2022, 75 (10) 658-662; DOI: 10.1136/jclinpath-2021-207631
Idylla MSI test as a new tool for microsatellite instability detection in sebaceous tumours and keratoacanthomas
Loëtitia Favre, Ruiqian Chen, Yaëlle Bellahsen-Harrar, Nicolas Ortonne, Anaïs Pujals

Journal of Clinical Pathology Oct 2022, 75 (10) 675-680; DOI: 10.1136/jclinpath-2021-207606
Molecular heterogeneity of pancreatic intraductal papillary mucinous neoplasms and implications for novel endoscopic tissue sampling strategies
Charlotte Vestrup Rift, Linea Cecilie Melchior, David Scheie, Carsten Palnæs Hansen, Eva Løbner Lund, Jane Preuss Hasselby

Journal of Clinical Pathology Oct 2022, 75 (10) 681-686; DOI: 10.1136/jclinpath-2021-207598
Nationwide evaluation of mutation-tailored anti-EGFR therapy selection in patients with colorectal cancer in daily clinical practice
Elisabeth M P Steeghs, Geraldine R Vink, Marloes A G Elferink, Quirinus J M Voorham, Hans Gelderblom, Iris D Nagtegaal, PATH Consortium Members, Katrien Grünberg, Marjolijn J L Ligtenberg

Journal of Clinical Pathology Oct 2022, 75 (10) 706-711; DOI: 10.1136/jclinpath-2021-207865
Gene of the month: Cornulin
Rajandeep Kaur, Anshika Chauhan, Shabir Ahmad Bhat, Debajyoti Chatterjee, Sushmita Ghoshal, Arnab Pal

Journal of Clinical Pathology May 2022, 75 (5) 289-291; DOI: 10.1136/jclinpath-2021-208011
Rapid EGFR evaluation from used H&E, IHC and FISH diagnostic slides with the Idylla platform
Josè Nunnari, Paolo Graziano, Lucia Anna Muscarella, Antonio Rossi, Lucia Rosalba Grillo, Giuseppe Montrone, Angela Di Lorenzo, Monica Bronzini, Alvaro Leone

Journal of Clinical Pathology May 2022, 75 (5) 338-344; DOI: 10.1136/jclinpath-2020-207315

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