Abstract
T lymphocytes are relatively quiescent cells, poised in the G0 stage of the cell cycle, until they encounter antigen. The initiation of an immune response by T cells requires the recognition of antigen by the T cell antigen receptor (TCR) and the conversion of this recognition event into biochemical signals that can induce a cellular response. This cellular response leads to the clonal expansion of antigen-specific differentiated effector T cells.
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Weiss, A. et al. (1994). Molecular and Genetic Insights Into T Cell Antigen Receptor Signal Transduction. In: Gupta, S., Paul, W.E., DeFranco, A., Perlmutter, R.M. (eds) Mechanisms of Lymphocyte Activation and Immune Regulation V. Advances in Experimental Medicine and Biology, vol 365. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0987-9_6
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DOI: https://doi.org/10.1007/978-1-4899-0987-9_6
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