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Mapping of the humanGSPT1 gene, a human homolog of the yeastGST1 gene, to chromosomal band 16p13.1

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Somatic Cell and Molecular Genetics

Abstract

TheGSPT1 gene, a human homolog of the yeastGST1 gene (formerly namedGST1-Hs), was mapped on human chromosome 16p13.1 by a combination of nonradioactive in situ hybridization and Giemsa staining. Southern blot hybridization with a panel of human-rodent somatic cells confirmed the location of theGSPT1 gene on chromosome 16 and also showed the existence of a homologous gene on the X chromosome. A breakpoint for nonrandom chromosome rearrangements has been found in the region ofGSPT1 in patients with acute nonlymphocytic leukemia.

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Ozawa, K., Murakami, Y., Eki, T. et al. Mapping of the humanGSPT1 gene, a human homolog of the yeastGST1 gene, to chromosomal band 16p13.1. Somat Cell Mol Genet 18, 189–194 (1992). https://doi.org/10.1007/BF01233164

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  • DOI: https://doi.org/10.1007/BF01233164

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