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Lactobacillus gasseri as the cause of septic urinary infection

Urosepsis durch Lactobacillus gasseri

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Summary

A 66-year-old patient developed severe urinary stasis due to a concrement in his right ureter; foudroyant septicemia followed.Lactobacillus gasseri was grown from pyoid urine from the right renal pelvis and in two blood cultures, thus suggesting septic urinary infection caused by lactobacilli. The infection was cured by catheterisation of the right ureter and antibiotic treatment with cefotaxime and amoxicillin. The concrement was removed by dissolution. Diabetes and urinary stasis appear to be the main predisposing factors for this exceptional case of septic urinary infection caused byL. gasseri.

Zusammenfassung

Bei einem 66jährigen Mann entwickelte sich infolge eines Uretersteins rechts eine schwere Harnabflußstörung mit foudroyant-septischem Krankheitsbild. Da sowohl in dem eitrigen Urin des gestauten rechten Nierenbeckens als auch in zwei BlutkulturenLactobacillus gasseri nachgewiesen werden konnte, muß eine Urosepsis durch Laktobakterien angenommen werden. Durch Ureterenkatheterisierung und antibiotische Therapie mit Cefotaxim und Amoxicillin konnte die Sepsis beherrscht werden. Das Konkrement wurde medikamentös aufgelöst. Diabetes und Harnstau dürften die entscheidenden prädisponierenden Faktoren für diesen ungewöhnlichen Fall einer Urosepsis durchL. gasseri sein.

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Literature

  1. Rogosa, M., Sharpe, M. E. Species differentiation of human vaginal lactobacilli. J. Gen. Microbiol. 23 (1960) 197–201.

    Article  CAS  PubMed  Google Scholar 

  2. Werner, H. Die gramnegativen anaeroben sporenlosen Stäbchen des Menschen. In:Bieling, R., Kathe, J., Köhler, W., Mayr, A. (eds.): Infektionskrankheiten und ihre Erreger. Fischer, Jena 1968, pp. 80–85.

    Google Scholar 

  3. Köhler, W., Mochmann, H. Grundriß der medizinischen Mikrobiologie. VEB Gustav Fischer Verlag, Jena 1975, p. 326.

    Google Scholar 

  4. Seeliger, H. P. R. Taschenbuch der medizinischen Bakteriologie. Urban und Schwarzenberg, München, Wien, Baltimore 1978, p. 132.

    Google Scholar 

  5. Biocca, E., Seppilli, A. Human infections caused by lactobacilli. J. Infect. Dis. 81 (1947) 112–115.

    Article  CAS  PubMed  Google Scholar 

  6. Howitt, B., Van Meter, M. Lesions produced in rabbits by lactobacillus cultures. J. Infect. Dis. 46 (1930) 368–383.

    Article  Google Scholar 

  7. Jay, P., Crowley, M., Hadley, F. P., Bunting, R. W. Bacteriologic and immunologic studies on dental caries. J. Am. Dent. Assoc. 20 (1933) 2130–2132.

    Google Scholar 

  8. Rosan, B., Hammon, B.-F. Toxicity ofLactobacillus casei. J. Dent. Res. 44 (1965) 783–785.

    Article  CAS  PubMed  Google Scholar 

  9. Sims, W. A pathogenic lactobacillus. J. Pathol. Bacteriol. 87 (1964) 99–105.

    Article  CAS  PubMed  Google Scholar 

  10. Attebery, H. R., Finegold, S. M. A new anaerobic blood culture system. 10th International Congress of Microbiology, Cindad de Mexico, 9–15 August 1970. J. Med. Microbiol. 6 (1973) 281–286.

    Article  Google Scholar 

  11. Canby, C. P., Bernier, J. L. Bacteriologic studies of carious dentine. J. Am. Dent. Assoc. 23 (1936) 2083–2089.

    Google Scholar 

  12. Jay, P., Voorhees, R. C. Bacillus acidophilus and dental caries. Dent. Cosmos 69 (1927) 977–980.

    Google Scholar 

  13. Steinle, C. J., Madonia, J. V., Bahn, A. N. Relationship of lactobacilli to the carious lesion. J. Dent. Res. 46 (1967) 191–196.

    Article  CAS  PubMed  Google Scholar 

  14. Wilson, G. S., Miles, A. A. Topley and Wilson's principles of bacteriology and immunity. 5th ed. Williams and Wilkins, Baltimore 1964, p. 168.

    Google Scholar 

  15. Axelrod, J., Keusch, G. T., Bottone, E., Cohen, S.-M., Hirschmann, C. Z. Endocarditis caused byLactobacillus plantarum. Ann. Intern. Med. 78 (1973) 33–37.

    Article  CAS  PubMed  Google Scholar 

  16. Bayer, A. S., Chow, A. W., Betts, D., Guze, L. B. Lactobacillemia — report of nine cases. Important clinical and therapeutic considerations. Am. J. Med. 64 (1978) 808–813.

    Article  CAS  PubMed  Google Scholar 

  17. Berger, U., Lutz, P., Sievers, C. Endocarditis lenta durchLactobacillus salivarius subsp.salicinicus. Dtsch. Med. Wochenschr. 101 (1976) 1349–1350.

    Article  CAS  PubMed  Google Scholar 

  18. Biocca, E., Reitano, D. Endocardite mortal no homen produzide pro un lactobacilo. Arg. Inst. Biol. (Sao Paulo) 27 (1943) 1–7.

    Google Scholar 

  19. Bourne, K. A., Beebe, J. L., Lue, Y. A., Ellner, P. D. Bacteremia due to bifidobacterium, eubacterium or lactobacillus; Twenty-one cases and review of the literature. Yale J. Biol. Med. 51 (1978) 505–512.

    CAS  PubMed  PubMed Central  Google Scholar 

  20. Dietzsch, J. Subakute bakterielle Endocarditis durch Laktobacillen beim Kinde. Monatsschr. Kinderheilkd. 103 (1955) 240–243.

    CAS  PubMed  Google Scholar 

  21. Dupont, B., Lapresle, C. L. Maladie D'Osler à lactobacille. Nouv. Presse Méd. 6 (1977) 3627–3628.

    CAS  PubMed  Google Scholar 

  22. Duval, J., Gasser, F., Ducan, H., Mora, M. Un nouveau cas d'endocardite infectieuse due à un lactobacille. Méd. Mal. Infect. 3 (1973) 371–377.

    Article  Google Scholar 

  23. Fritsche, D., Mennicken, U., Vielhaber, K. Die Endocarditis durch opportunistische Coryne- und Lactobacterien. Dtsch. Med. Wochenschr. 98 (1973) 2239–2242.

    Article  CAS  PubMed  Google Scholar 

  24. Horeau, J., Nicolas, G., Courtieux, A., Bouhour, J.-B., Menuet, J. C. A propos d'un cas d'endocardite due à un lactobacillus. Ann. Méd. Interne 120 (1969) 125–129.

    CAS  Google Scholar 

  25. Isenberg, D. Lactobacillus infective endocarditis. Proc. Roy. Soc. Med. 70 (1977) 278–280.

    CAS  PubMed  PubMed Central  Google Scholar 

  26. Jeandet, J. C. A propos d'un cas de maladie d'Osler due au lactobacillus. Thèse de Médecine, Editions AGEMP, Paris 1963.

    Google Scholar 

  27. Marschall, F. Der DöderleinscheBacillus vaginalis als Endocarditis-Erreger. Zbl. Bakt. I. Abt. Orig. 141 (1938) 153–159.

    Google Scholar 

  28. Seneca, H., Grant, J. P. Gram-negative sepsis and endotoxic shock. Antibiot. Chemother. 21 (1976) 52–62.

    Article  CAS  PubMed  Google Scholar 

  29. Sharpe, M. E., Hill, R., Lapage, S. P. Pathogenic lactobacilli. J. Med. Microbiol. 6 (1973) 281–286.

    Article  CAS  PubMed  Google Scholar 

  30. Tenenbaum, M. J., Warner, J.-F. Lactobacillus casei endocarditis. Ann. Intern. Med. 82 (1975) 539.

    Article  Google Scholar 

  31. Baltch, A. L., Buhac, J., Agrawal, A., O'Connor, P., Bram, M., Malatino, E. Bacteremia after upper gastrointestinal endoscopy. Arch. Intern. Med. 137 (1977) 594–597.

    Article  CAS  PubMed  Google Scholar 

  32. Rogosa, M. Gram-positive asporogenous rod-shaped bacteria. In:Buchanan, R. E., Gibbons, N. E. (eds.): Bergey's manual of determinative bacteriology. Williams & Wilkins, Baltimore 1974, pp. 576–593.

    Google Scholar 

  33. Lauer, E., Kandler, O. Lactobacillus gasseri sp. nov., a new species of the subgenusThermobacterium. Zbl. Bakt. I. Abt. Orig. C 1 (1980) 75–78.

    Google Scholar 

  34. Lauer, E., Helming, C. H., Kandler, O. Heterogeneity of the speciesLactobacillus acidophilus (Moro) Hansen and Mocquot as revealed by biochemical characteristics and DNA-DNA hybridisation. Zbl. Bakt. Hyg. I. Abt. Orig. C 1 (1980) 150–168.

    CAS  Google Scholar 

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Dickgießer, U., Weiss, N. & Fritsche, D. Lactobacillus gasseri as the cause of septic urinary infection. Infection 12, 14–16 (1984). https://doi.org/10.1007/BF01641017

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