Summary
In recent years, the cardiovascular manifestations of systemic lupus erythematosus have became more apparent as a consequence of both prolonged survival and improvement in diagnostic modalities. We report the case of a 16-year old woman with systemic lupus erythematosus in whom the presence of cardiomyopathy was characterized by endomyocardial biopsy. This diagnostic technique also showed that the histologic hall-mark of lupus myocardiopathy persisted despite corticosteroid and plasmapheresis, suggesting the need of a careful cardiac follow-up in these patients.
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References
Weiss, M.B. Right ventricular biopsy. In: Endomyocardial Biopsy: techniques and applications, Editor: Fenoglio J.J. Jr., CRC Press, Boca Raton, Florida, 1982, 8–13.
Borestein, D.G., Fye, W.B., Arnet, F.C., Sevens, M.B. Myocarditis of SLE: Association with myocarditis. Ann Intern Med 1978, 89, 619–624.
Bidani, A.K., Robert, J.L., Schwartz, M.M., Lewis, E.J. Immunopathology of cardiac lesions in fatal SLE. Am J Med 1980, 69, 849–58.
Ansari, A., Larson, P.H. Heart disease in systemic lupus erythematosus: diagnosis and management. Texas Heart Inst J 1985, 12, 9–21.
Ansari, A., Larson, P.H., Bates, H.D. Cardiovascular manifestations of systemic lupus erythematosus: current perspective. Prog. Cardiovasc Dis 1985, 27(6), 421–34.
Doherty, N.E., Slegel, R.J. Cardiovascular manifestation of systemic lupus erythematosus. Am Heart J 1985, 110, 1257–65.
Bridgnem, W., Baywaters, G.L., Lessof, M.H., Ross, I.P. The heart in systemic lupus erythematosus. Br Heart J 1960, 22, 1–16.
Kong, T.O., Kellum, R.E., Haserick, J.R. Clinical diagnosis of cardiac involvement in systemic lupus erythematosus: a correlation of clinical and autopsy findings in thirty patients. Circulation 1962, 26, 7–11.
Jones, J. Plasmapheresis in SLE, Clin Reum Dis 1982, 8, 243–46
Urowitz, M.B., Bookman A.A.M., Koehler, B.E., Gordon, D.A., Smythe, H.A., Ogryzlo, M.A. The bimodal mortality pattern of systemic lupus erythematosus. Am J Med 1976, 60, 221–25.
Del Rio, A., Vasquez, J.J., Sobrino, J.A., Gil, A., Barbado, J., Mate, I., Oritz-Vazquez, J. Myocardial involvment in systemic lupus erythematosus. Chest 1978, 74, 414–17.
Homcy, C.J., Liberthson, R.R., Fallon, J.T., Gross, S., Miller, L.M. Ischemic heart disease in systemic lupus erythematosus in the young patient. Am J Cardiol 1982, 49, 478–84.
Liberthson, R.R., Homcy, C., Fallon, J.T., Gross, S., Leppo, J., Miller, L. Systemic lupus erythematosus and heart disease. Primary Cardiol 1983, 9, 77–81.
Strauer, B.E., Brune, I., Schenk, H., Knoll, D., Perinos, I. Lupus cardiomyopathy: cardiac mechanics, hemodynamics and coronary blood flow in uncomplicated systemic lupus erythematosus. Am heart J 1976, 92, 715–22.
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Tamburino, C., Fiore, C.E., Foti, R. et al. Endomyocardial biopsy in diagnosis and management of cardiovascular manifestations of systemic lupus erythematosus (SLE). Clin Rheumatol 8, 108–112 (1989). https://doi.org/10.1007/BF02031079
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DOI: https://doi.org/10.1007/BF02031079