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Bacteria closely resemblingHelicobacter pylori detected immunohistologically and genetically in resected gallbladder mucosa

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Abstract

A microorganism with close immunohistological and genetic resemblance toHelicobacter pylori was found in the resected gallbladder mucosa of a 41-year-old woman. The woman was admitted to hospital complaining of fever and right hypochondrial pain. Cholecystectomy was carried out under the diagnosis of gallstones and cholecystitis. A microorganism resemblingH. pylori (stained with H&E, Giemsa, and Wartin-Starry) was detected incidentally on pathological examination. The microorganism was also positive for immunohistochemical staining. An amplification reaction was seen on genetic examination by the polymerase chain reaction (PCR) method (urease β-genes). Our findings suggest thatH. pylori may be present in tissues other than gastric mucosa.

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References

  1. Warren JR. Unidentified curved bacilli on gastric epithelium in active chronic gastritis. Lancet 1983;I:1273–1275.

    Google Scholar 

  2. Marshall BJ, Warren JR. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet 1984;1:1311–1314.

    CAS  PubMed  Google Scholar 

  3. Parsonnet J, Friedman GD, Daniel MS, et al.Helicobacter pylori infection and the risk of gastric carcinoma. N Engl J Med 1991;325:1127–1131.

    CAS  PubMed  Google Scholar 

  4. Goodwin CS. Duodenal ulcer,Campylobacter pylori, and the “leaking roof” concept. Lancet 1988II:1467–1468.

    Google Scholar 

  5. Morris A, Nicholson G, Zai J, et al.Campylobacter pylori infection in Meckel's diverticula containing gastric mucosa. Gut 1989;30:1233.

    CAS  PubMed  Google Scholar 

  6. Westblom TU, Phadnis S, Normark S. Sensitivity of an assay for detection ofHelicobacter pylori in human saliva using polymerase chain reaction (PCR). Microb Ecol Health Dis 1991;4[Suppl.]:156.

    Google Scholar 

  7. Clayton CL, Kleanthous H, Coates PJ, et al. Sensitive detection ofHelicobacter pylori by using polymerase chain reaction. J Clin Microbiol 1992;30:192–200.

    CAS  PubMed  Google Scholar 

  8. Hayashi K, Tamura T, et al. Epidemiology and routes ofHelicobacter pylori infections. Jpn J Clin Med 1993;12:3114–3119.

    Google Scholar 

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Kawaguchi, M., Saito, T., Ohno, H. et al. Bacteria closely resemblingHelicobacter pylori detected immunohistologically and genetically in resected gallbladder mucosa. J Gastroenterol 31, 294–298 (1996). https://doi.org/10.1007/BF02389534

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  • DOI: https://doi.org/10.1007/BF02389534

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