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Familial tumoral calcinosis: association with cerebral and peripheral aneurysm formation

  • DIAGNOSTIC NEURORADIOLOGY
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Abstract

Two siblings with histologically and radiologically proven tumoral calcinosis presented with cerebral and peripheral aneurysms. The brother died of a ruptured subclavian artery aneurysm after surgical repair of brachial, iliofemoral and coeliac axis aneurysms. Magnetic resonance and catheter angiography in the sister demonstrated marked carotid dysplasia and a left ophthalmic segment aneurysm, not amenable to treatment. We believe this is the first reported case of familial aneurysms in association with tumoral calcinosis.

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Authors and Affiliations

  1. Department of Neuroradiology, Central Manchester Healthcare Trust, Oxford Road, Manchester M13 9WL, UK, e-mail: RDLaitt@aol.com, Tel.: + 44-161-2 76 42 33, Fax: + 44-161-2 76 80 85, , , , , , GB

    W. M. Adams & R. D. Laitt

  2. Department of Medicine, Central Manchester Healthcare Trust, Oxford Road, Manchester M13 9WL, UK, , , , , , GB

    M. Davies

  3. Department of Neuropathology, Central Manchester Healthcare Trust, Oxford Road, Manchester M13 9WL, UK, , , , , , GB

    D. G. O'Donovan

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  1. W. M. Adams
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  2. R. D. Laitt
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  3. M. Davies
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  4. D. G. O'Donovan
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Received: 19 April 1998 Accepted: 6 October 1998

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Adams, W., Laitt, R., Davies, M. et al. Familial tumoral calcinosis: association with cerebral and peripheral aneurysm formation. Neuroradiology 41, 351–355 (1999). https://doi.org/10.1007/s002340050763

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  • DOI: https://doi.org/10.1007/s002340050763

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