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Chondroblastoma in adult age

  • Original Article • CHONDROBLASTOMA - TUMORS
  • Published:
European Journal of Orthopaedic Surgery & Traumatology Aims and scope Submit manuscript

Abstract

Purpose

Chondroblastoma (CB) is a rare benign tumor that occurs most commonly in the second decade of life. No studies on CB in adulthood have been reported. Our purposes were to report a single-institution experience on CB in adults and to discuss the clinical and imaging findings, type of treatment, oncologic and functional outcomes.

Patients and methods

All patients diagnosed and treated for CB from 1981 to 2014 were reviewed. The main inclusion criterion was patients above their 30 years of age at diagnosis. Clinical presentation, imaging, surgical treatment, complications and functional outcome were evaluated. Local recurrences were recorded.

Results

There were 15 males (65%) and 8 females (35%) with a mean age of 40 years (range 30–59 years). Tumor involved the small bones (talus, calcaneus, acromion, cuneiform, metatarsals) in 15 patients (65%) and the long bones in eight patients (35%). Treatment consisted of curettage only (6 cases), curettage plus phenol (13 cases), curettage plus radiotherapy (one patient with vertebral tumor), resection (two patients with CB of the acromion) and chopart amputation (one patient with a metatarsal tumor). At a mean follow-up of 8.4 years (range 3–30 years), twenty patients (87%) remained continuously disease-free, whereas three had local recurrences. None of the patients received chemotherapy.

Conclusion

This study confirms that the occurrence and outcome of adult patients with CB are similar with those affecting younger patients. The main difference consists of the involved bones; flat bones and short tubular bones of the foot, especially the talus and calcaneus, are most commonly involved as opposed to long tubular bones.

Level of evidence

Therapeutic study, level IV-1 (case series).

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Authors and Affiliations

  1. Department of Orthopaedics and Orthopaedic Oncology, University of Padova, Via Giustiniani 3, 35128, Padua, Italy

    Andrea Angelini, Giulia Trovarelli, Antonio Berizzi & Pietro Ruggieri

  2. Department of Orthopaedic Surgery, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran

    Mohammad Hassani

  3. First Department of Orthopaedics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece

    Andreas F. Mavrogenis

  4. Department of Orthopaedic Oncology, Istituto Ortopedico Rizzoli, Bologna, Italy

    Carlo Romagnoli

Authors
  1. Andrea Angelini
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  2. Mohammad Hassani
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  3. Andreas F. Mavrogenis
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  4. Giulia Trovarelli
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  5. Carlo Romagnoli
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  6. Antonio Berizzi
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  7. Pietro Ruggieri
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Corresponding author

Correspondence to Pietro Ruggieri.

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Conflict of interest

None of the authors have any financial and personal relationships with other people or organizations that could inappropriately influence (bias) their work. Dr. Angelini, Dr. Hassani, Dr. Mavrogenis, Dr. Trovarelli, Dr. Romagnoli, Dr. Berizzi and Prof. Ruggieri have nothing to disclose.

Ethic committee statement

Each author certifies that the manuscript has been read and approved and that the manuscript represents honest work. The IRB approval has not been requested due to the retrospective nature of the study, according to the policy of Ethic Committee of our Institute.

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Angelini, A., Hassani, M., Mavrogenis, A.F. et al. Chondroblastoma in adult age. Eur J Orthop Surg Traumatol 27, 843–849 (2017). https://doi.org/10.1007/s00590-017-1996-7

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  • DOI: https://doi.org/10.1007/s00590-017-1996-7

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