Adenoid cystic carcinoma of major and minor salivary glands

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Abstract

The records of eighty-one patients with adenoid cystic carcinoma of major and minor salivary glands at Roswell Park Memorial Institute have been reviewed. Survival data on sixty-five patients followed five years or more reveals an average survival of 7.4 years. Sixty-five per cent (forty-two of sixty-five patients) lived for five years, 31 per cent (twenty of sixty-five) for ten years, and 15 per cent (ten of sixty-five) for fifteen years or longer. The patients were divided into four anatomic groups which regionally involve similar problems in treatment and often result in similar cosmetic and functional deformities. Similarities are seen but there are also some notable differences in recurrences and total survival depending on the anatomic location of the primary lesion.

Aggressive surgical resection and reconstruction is the preferred method of therapy for both primary and locally recurrent disease whenever possible. Local recurrences and systemic metastases are common, but are often delayed for several years. Locally recurrent tumor can be controlled in many instances by surgical resection or radiotherapy, but careful lifetime follow-up study of the patient is required to discover recurrent disease at its earliest stage.

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Presented at the Seventeenth Annual Meeting of the Society of Head and Neck Surgeons, Vancouver, British Columbia, May 10–12, 1971.

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